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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10946 |
D4-abiraterone
Abiraterone D4A metabolite,CB-7627,Δ4-Abiraterone |
Androgen Receptor | Endocrinology/Hormones |
D4-Abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid 5a-reductase (SRD5A), the main metabolite of abiraterone. D4-Abiraterone is also an antagonist of androgen receptor. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01337 |
DLL4 Protein, Mouse, Recombinant (His)
Dll4,δ4,delta-like 4 (Dr... |
Mouse | HEK293 Cells |
DLL4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.7 kDa and the accession number is Q9JI71. | |||
TMPY-05796 |
DLL4 Protein, Mouse, Recombinant (mFc)
δ4,Dll4,delta-like 4 (Dr... |
Mouse | HEK293 Cells |
DLL4 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 80.61 kDa and the accession number is Q9JI71. | |||
TMPK-00360 |
DLL4 Protein, Human, Recombinant (His & Avi)
notch ligand DLL4,MGC126344,δ-lik... |
Human | HEK293 Cells |
Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibit... |