Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04722 |
DcR1/TRAILR3 Protein, Human, Recombinant (His)
TRAILR3,TRID,DCR1,TRAIL-R3,CD263,DCR |
Human | HEK293 Cells |
TNFRSF10C CNV in patients with CRC is associated with distant metastatic disease. A high frequency of CGI methylation in the TNFRSF10C promoter results in inactivation of the gene and enhancement of tumor growth in most PC cell lines (except CFPAC-1). Inactivation of TNFRSF10C by CpG island (CGI) hypermethylation can play an important role in PC progression and be potentially useful as a diagnostic marker and a new therapeutic approach for PC. | |||
TMPJ-00418 |
TRAIL R3/TNFRSF10C Protein, Human, Recombinant (hFc & His)
Decoy Receptor 1,Antagonist Decoy Receptor for TRAI... |
Human | HEK293 Cells |
Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesn’t transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis. | |||
TMPK-00248 |
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi)
DCR2,TNFRSF10D,RSF10D,CD264,TRUND... |
Human | HEK293 Cells |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 19.4 kDa and t... | |||
TMPK-00249 |
TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated
TNFRSF10D,CD264,TRUNDD,DCR2,RSF10... |
Human | HEK293 Cells |
TNF-related apoptosis inducing ligand (TRAIL) is a potential antitumor protein known for its ability to selectively eliminate various types of tumor cells without exerting toxic effects in normal cells and tissues. TRAIL-R2/DR5 as well as TRAIL-R3/DcR1 and TRAIL-R4/DcR2 were significantly higher expressed in advanced tumour stages. TRAIL R4/TNFRSF10D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is ... |