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3

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T27189 DL-threo dihydrosphingosine

DL-Safingol,DTD,DL threo dihydrosphingosine

DL-threo dihydrosphingosine is a cell-permeable inhibitor of the extracellular signal-regulated kinase (ERK) signalling cassette in mammalian cells. DL-threo dihydrosphingosine is effective against both growth factor- and G-protein-dependent activation of
T79039 GGGDTDTC-Mc-vc-PAB-MMAE

GGGDTDTC-Mc-vc-PAB-MMAE为一种ADC药物-连接物偶联物,主要由微管蛋白抑制剂Monomethylauristatin E (MMAE)组成。
TP1460 NH2-KLGADTDGEQDQHMTYGGQ-COOH

NH2-QGGYTMHQDQEGDTDAGLK-COOH is a synthetic peptide chain consisting of a primary amine group attached to lysine and a carboxyl group attached to glutamine.

化合物

DL-threo dihydrosphingosine
Cat.No: T27189
Synonym: DL-Safingol,DTD,DL threo dihydrosphingosine
Target:
GGGDTDTC-Mc-vc-PAB-MMAE
Cat.No: T79039
Synonym:
Target:
NH2-KLGADTDGEQDQHMTYGGQ-COOH
Cat.No: TP1460
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN5336 9-Oxo-10,11-dehydroageraphorone

4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone,泽兰二酮

9-Oxo-10,11-dehydroageraphorone has acaricidal activity. It induces hepatotoxicity and cholestasis in rats. 9-Oxo-10,11-dehydroageraphorone also effectively inhibits the proliferation of HeLa cells by arresting the cell cycle transition from S to G2/M pha

天然产物

9-Oxo-10,11-dehydroageraphorone
Cat.No: TN5336
Synonym: 4,7(11)-Cadinadiene-3,8-dione,DTD,7,11-Dehydro-8-oxoageraphorone,泽兰二酮
Target:
Cat. No. Product Name Species Expression System
TMPY-03407 NQO1 Protein, Human, Recombinant (His)

NAD(P)H dehydrogenase, quinone 1,NMORI,DIA4,QR1,NMOR1,DT...

Human E. coli
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-electron reduction of quinones that results in the production of radical species. Mutations in the NQO1 gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered ex...
TMPJ-01241 DTD1 Protein, Human, Recombinant (His)

DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-...

Human HEK293 Cells
D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens...

重组蛋白

NQO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03407
Species: Human
Expression System: E. coli
DTD1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01241
Species: Human
Expression System: HEK293 Cells
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