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Cat. No. Product Name Target Signaling Pathways
T16392 ONC206

Dopamine Receptor GPCR/G Protein; Neuroscience
ONC206 是一种 ONC201 的类似物,是一种多巴胺 D2- 样受体 (DRD2/3/4) 的选择性拮抗剂,其拮抗作用在纳摩尔级别。它具有广谱抗肿瘤活性。
T9228 Propionylpromazine hydrochloride

盐酸丙酰丙嗪,Propiopromazine hydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) 是多巴胺受体 D2 (DRD2) 拮抗剂,可用于研究帕金森氏病。
T69513 (–)-IHCH7041

(–)-IHCH7041 is a optical rotation negative isomer of IHCH7041. (–)-IHCH7041 is a DRD2 partial agonist. (–)-IHCH7041 showed EC50 = 1.38 nM in Gαi1–γ9 dissociation and 2.75 nM in β-arrestin2 recruitment. (–)-IHCH7041 exhibited a inhibition constant (Ki) of 22.44 nM binding affinity at DRD2. (–)-IHCH7041 has antidepressant properties and reverses cognitive impairment.
T69512 IHCH7041

IHCH7041, also known as (+/-)-IHCH7041, is a DRD2 partial agonist. IHCH7041 contains two enantiomers: (-)-IHCH7041 and (+)-IHCH7041 (optical rotation negative and positive). (+/-)-IHCH7041 has CAS#2813335-29-2. Two isomers have CAS#2813335-07-6 (rotation negative) and 2813335-06-5 (rotation positive), respectively.

化合物

ONC206
Cat.No: T16392
Synonym:
Target: Dopamine Receptor
Propionylpromazine hydrochloride
Cat.No: T9228
Synonym: 盐酸丙酰丙嗪,Propiopromazine hydrochloride
Target: Dopamine Receptor
(–)-IHCH7041
Cat.No: T69513
Synonym:
Target:
IHCH7041
Cat.No: T69512
Synonym:
Target:
TargetMol Loading
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