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抑制剂 & 化合物

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天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9409	Mesdopetam hemitartrate IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Mesdopetam hemitartrate (IRL790 hemitartrate) 是一种多巴胺D3受体拮抗剂 (Ki=90 nM;IC50=9.8 μM)，具有稳定精神运动的作用，可用于帕金森病的运动和精神并发症的研究。
T38828	Mesdopetam IRL790
	Mesdopetam (IRL790) is a dopamine D3 receptor antagonist with a Ki of 90 nM and an IC50 of 9.8 μM for the human recombinant D3 receptor. It exhibits psychomotor stabilizing properties and is utilized in the study of motor and psychiatric complications associated with Parkinson's disease.
T37533	DOPAL
	DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson's disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as wel...

化合物

Mesdopetam hemitartrate

Cat.No: T9409

Synonym: IRL790 hemitartrate,1-Propanamine, N-[2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)

Target: Dopamine Receptor

Cat.No: T38828

Synonym: IRL790

Cat.No: T37533

Cat. No.	Product Name	Target	Signaling Pathways
T3412	Hydroxytyrosol 2-(3,4-Di-hydroxyphenyl)-ethanol,3-Hydroxytyrosol,Dihydroxyphenylethanol,羟基酪醇,3,4-dihydroxyphenylethanol	Others; Endogenous Metabolite; Antibacterial; Antifungal	Metabolism; Microbiology/Virology; Others
	Hydroxytyrosol (2-(3,4-Di-hydroxyphenyl)-ethanol) 是从橄榄树及其叶子中提取的一种酚类化合物，具有抗氧化、抗动脉粥样硬化、抗血栓、抗菌、抗炎和抗肿瘤的作用，可用于研究心血管药物。

天然产物

Cat.No: T3412

Synonym: 2-(3,4-Di-hydroxyphenyl)-ethanol,3-Hydroxytyrosol,Dihydroxyphenylethanol,羟基酪醇,3,4-dihydroxyphenylethanol

Target: Others, Endogenous Metabolite, Antibacterial, Antifungal

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