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Cat. No. Product Name Target Signaling Pathways
T71805 DOCK5-IN-C21

DOCK5-IN-C21 is an allosteric inhibitor of the guanine nucleotide exchange factor DOCK5.
T8527 CPYPP

Others Others
CPYPP 是DOCK2-Rac1相互作用的抑制剂。它能够结合DOCK2DHR-2结构域,并以剂量依赖性方式抑制 DOCK2DHR-2 (IC50:22.8 µM) 对 Rac1 的鸟嘌呤核苷酸交换因子活性。它还抑制DOCK180和DOCK5,对 DOCK9 的抑制作用较小。
T69656 E197

E197 is a DOCK5 inhibitor. E197 can inhibit both mouse and human osteoclast activity. In particular, E197 prevented pathological bone loss in mice. Most interestingly, treatment with E197 did not affect osteoclast and osteoblast numbers and hence did not impair bone formation. E197 could represent a lead molecule to develop new antiosteoporotic drugs targeting the mechanism of osteoclast adhesion onto the bone.

化合物

DOCK5-IN-C21
Cat.No: T71805
Synonym:
Target:
CPYPP
Cat.No: T8527
Synonym:
Target: Others
E197
Cat.No: T69656
Synonym:
Target:
TargetMol Loading
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