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Targets Recommended: Others

5

抑制剂 & 化合物

1

天然产物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T19287 TPGS-750-M

DL-alpha-Tocopherol methoxypolyethylene glycol succinate

Others Others
DL-α-tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) is a hydrophilic lipid molecule that acts as a surfactant.
T19292 DL-threo-2-methylisocitrate

Others Others
dl-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). IC50 value: target: using michael-menten nonlinear least squares fitting to determine the purified recombinant ICL1's Km for threo-D(s)L(s)-isocitrate (ICA) is 188°M and kcat is 5.24
T36989 N-3-hydroxydecanoyl-DL-Homoserine lactone

N-3-hydroxydecanoyl-DL-Homoserine lactone is a bacterial quorum-sensing molecule.1It activates SdiA (EC50= 0.6 μM), a transcription factor that detects N-acyl homoserine lactones (AHLs), in the 14028/pJNS25 strain ofS. enterica.2 1.Fekete, A., Frommberger, M., Rothballer, M., et al.Identification of bacterial N-acylhomoserine lactones (AHLs) with a combination of ultra-performance liquid chromatography (UPLC), ultra-high-resolution mass spectrometry, and in-situ biosensorsAnal. Bioanal. Chem.387...
T36974 D-threo-PPMP hydrochloride

D-threo-PPMP is a glucosylceramide (GlyCer) synthetase inhibitor.1,2It is the active enanantiomer and enzymatic inhibitory component of the racemic DL-threo-PPMP . In MDCK kidney epithelial cells, D-threo-PPMP induces a 70% reduction in cell growthin vitroat 20 μM and significantly inhibits DNA synthesis at 3 μM.3[Matreya, LLC. Catalog No. 1865] 1.Shen, W., Henry, A.G., Paumier, K.L., et al.Inhibition of glucosylceramide synthase stimulates autophagy flux in neuronsJ. Neurochem.129(5)884-894(201...
T83898 S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine

SFN-Cys,D,L-Sulforaphane-L-cysteine

S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine (SFN-Cys) 是一种异硫氰酸酯衍生物及第一类和第二类组蛋白去乙酰化酶(HDAC)抑制剂和抗癌剂硫代硫酸烯醇醚的活性代谢产物。它通过巯基乙酸途径酶从硫代硫酸烯醇醚经DL-硫代硫酸烯醇醚谷胱甘肽和硫代硫酸烯醇醚半胱氨酸甘肽中间体形成。SFN-Cys (20 µM) 通过创伤愈合和腔室分析实验,分别减少了U87MG和U373 MG胶质母细胞瘤细胞的侵袭和迁移。在45 µM的浓度下,它降低了对紫杉醇耐药的A549肺癌细胞(A549/T)中的α-微管蛋白、βIII-微管蛋白、司他敏1和X连锁抑制剂的凋亡(XIAP)的水平,并减少了细胞密度。使用30 µM浓度的SFN-Cys诱导U87MG和U373 MG细胞凋亡和G2/M期细胞周期停滞。

化合物

TPGS-750-M
Cat.No: T19287
Synonym: DL-alpha-Tocopherol methoxypolyethylene glycol succinate
Target: Others
DL-threo-2-methylisocitrate
Cat.No: T19292
Synonym:
Target: Others
N-3-hydroxydecanoyl-DL-Homoserine lactone
Cat.No: T36989
Synonym:
Target:
D-threo-PPMP hydrochloride
Cat.No: T36974
Synonym:
Target:
S-(N-Methylsulfinylbutylthiocarbamoyl)-L-cysteine
Cat.No: T83898
Synonym: SFN-Cys,D,L-Sulforaphane-L-cysteine
Target:
Cat. No. Product Name Target Signaling Pathways
T13654 DL-m-Tyrosine

Others Others
DL-m-Tyrosine shows effects on Arabidopsis root growth.

天然产物

DL-m-Tyrosine
Cat.No: T13654
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPK-01062 RGMC Protein, Mouse, Recombinant (His)

HJV,DL-M,JH,Rgmc,RGM-C,Hemojuvelin,HFE2,HFE2AMGC239...

Mouse HEK293 Cells
RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C),both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system.

重组蛋白

RGMC Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01062
Species: Mouse
Expression System: HEK293 Cells
TargetMol Loading
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