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Cat. No. | Product Name | Target | Signaling Pathways |
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T69437 |
NDJ18
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NDJ18 is a potent and selective SIRT2 inhibitor which validated the in silico protocol and opened up the possibility for generalization and broadening of its application. The anticancer effects of the most potent compound NDJ18 were examined on the triple-negative breast cancer cell line. Results indicated that NDJ18 represents a promising structure suitable for further evaluation. | |||
T24005 |
DJ101
DJ-101,DJ 101 |
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DJ101is an effective and metabolically stable inhibitor of tubulin. It can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors. | |||
T62174 |
Protein deglycase DJ-1 against-1
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Protein deglycase DJ-1 against-1 是一种能够透过血脑屏障的 DJ-1 结合化合物,依赖地靶向 DJ1。Protein deglycase DJ-1 against-1 是一种神经保护剂,具有潜力进行帕金森病的研究。 | |||
T82667 |
CRT0063465
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CRT0063465是一种同时针对人类PGK1和Stress Sensor DJ1的配体,其对PGK1的Kd值为24 μM。该化合物能够调节端粒蛋白复合体的形成及端粒长度。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-02043 |
PARK7/DJ-1 Protein, Human, Recombinant (His)
DJ1,HEL-S-67p,DJ-1,parki... |
Human | E. coli |
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress. PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress... |