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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T36921	16α-Hydroxyetiocholanolone
	16α-Hydroxyetiocholanolone is a metabolite of 16α-hydroxydehydroisoandrosterone (16α-DHEA) and androstenedione.1,2 1.Lai, E.Y., and Solomon, S.The in vivo metabolism of 16ɑ-hydroxydehydroisoandrosterone in manBiochemistry6(7)2040-2052(1967) 2.Christakoudi, S., Cowan, D.A., Christakudis, G., et al.21-hydroxylase deficiency in the neonate - trends in steroid anabolism and catabolism during the first weeks of lifeJ. Steroid Biochem. Mol. Biol.138334-347(2013)
T2195L	Epiandrosterone Sulfate Epiandrosterone 16-bromo,Epiandrosterone
	Epiandrosterone sulfate is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase of the adrenal hormone DHEA.
T73779	5β-Androstan-3β-ol-17-one
	5β-Androstan-3β-ol-17-one（3β-Etiocholanolone；5β-Epiandrosterone），为5β还原型类固醇，主要是脱氢表雄酮（DHEA）的关键代谢物之一。在C57BL/KsJ基因型糖尿病（db/db）小鼠中，该化合物显示出显著的降糖效果，并且具有对神经元的抑制活性。
T38028	(R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide
	N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Docosahexaenoyl ethanolamide (DHEA) has potential signaling roles in cancer, inflammation, and neurological development and functioning. At least some of DHEA's effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists and voltage-gated K+ channel blockers. (R)-(+)-Docosahexaenyl-1'-hydroxy-2'-propylamide is a homolog of DHEA,...
T72213	Efonidipine hydrochloride NZ-105 hydrochloride
	Efonidipine(NZ-105)盐酸盐是T 型和L 型钙离子通道双重阻断剂。
T36920	16α-hydroxy Dehydroepiandrosterone
	16α-hydroxy Dehydroepiandrosterone is a metabolite of the endogenous steroid hormone dehydroepiandrosterone .116α-hydroxy Dehydroepiandrosterone is formed from dehydroepiandrosteronevia16-hydroxylation by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in adult human liver microsomes, as well as by fetal recombinant CYP3A7. It is a precursor to fetal estrogens, including estriol .2 1.Miller, K.K.M., Cai, J., Ripp, S.L., et al.Stereo- and regioselectivity account for the diversity of dehydro...

化合物

16α-Hydroxyetiocholanolone

Cat.No: T36921

Synonym:

Target:

Epiandrosterone Sulfate

Cat.No: T2195L

Synonym: Epiandrosterone 16-bromo,Epiandrosterone

Target:

5β-Androstan-3β-ol-17-one

Cat.No: T73779

Synonym:

Target:

(R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide

Cat.No: T38028

Synonym:

Target:

Efonidipine hydrochloride

Cat.No: T72213

Synonym: NZ-105 hydrochloride

Target:

16α-hydroxy Dehydroepiandrosterone

Cat.No: T36920

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T26366	Dehydroepiandrosterone sulfate PB 005,PB005,Prasterone sulfate,DHEA sulfate,DHEAS,PB-005	Others	Others
	Dehydroepiandrosterone sulfate (PB-005) 影响神经元的迁移、树突的分枝和新突触的形成。
T0856	Dehydroisoandrosterone 3-acetate Dehydroepiandrosterone 3-acetate,Dehydroepiandrosterone acetate,Prasterone acetate,DHEA acetate,醋酸去氢表雄酮,androstenolone acetate	Androgen Receptor	Endocrinology/Hormones
	Dehydroisoandrosterone 3-acetate (Prasterone acetate) 是一种雄性激素/雌性激素的前体物质，是一种由肾上腺皮质产生的主要 C19 类固醇，能够调节脊椎动物的攻击性行为。
T10048	17a-Hydroxypregnenolone	Endogenous Metabolite	Metabolism
	17a-Hydroxypregnenolone 是一种孕烷类固醇, 是形成脱氢表雄酮的激素原。