Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22720 |
3,3'-Difluorobenzaldazine
DFB |
Others | Others |
allosteric potentiator of mGlu5 | |||
T22711 |
DCB
3,3'-dichlorobenzaldazine |
Others; GluR | Neuroscience; Others |
DCB (3,3'-dichlorobenzaldazine) 是 mGluR5 的变构配体,显示出 3,3'-二甲氧基苯扎嗪 (DMeOB) 的负调节作用。 DCB 在 3,3'-二氟苯扎嗪 (DFB) 的帮助下阻断 mGluR 的正变构调节。 | |||
T61818 | DFBTA | ||
DFBTA is a highly effective and orally active inhibitor of ANO1, specifically the calcium-activated chloride channel anoctamin-1. It exhibits potent inhibitory activity, with an IC 50 of 24 nM. Notably, DFBTA demonstrates significant analgesic efficacy in treating inflammatory pain [1]. |