Cat. No. | Product Name | Target | Signaling Pathways |
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T82595 |
DEALA-Hyp-YIPD
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DEALA-Hyp-YIPD为HIF-1α抑制剂,阻断VHL/HIF-1α相互作用,显示IC50值为0.91 μM,Kd为180 nM。 | |||
T41172 |
FAM-DEALA-Hyp-YIPD
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FAM-DEALA-Hyp-YIPD is a fluorescent HIF-1α peptide (Kd= 180-560 nM). Can be used to assess VHL binding in Fluorescence Polarization (FP) displacement assay, and evaluate the effect of VHL binding on degradation activity. Excitation maximum = 485 nm, emission maximum = 535 nm. Longer peptide version, FAM-DEALAHypYIPMDDDFQLRSF, also available. | |||
T41173 |
FAM-DEALAHypYIPMDDDFQLRSF
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Others | Others |
FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluorescence polarization (FP) displacement assay. Excitation/emission maxima (λ) = 485/520 nm. This product is a longer peptide version of FAM-DEALA-Hyp-YIPD. |