Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5402 |
DDR1-IN-2
DDR1 inhibitor 7rh |
Discoidin Domain Receptor (DDR) | Tyrosine Kinase/Adaptors |
DDR1-IN-2 (DDR1 inhibitor 7rh) 是盘状结构域受体 1 抑制剂 (IC50:13.1 nM),对 DDR2 的抑制作用相对较弱 (IC50:203 nM)。 | |||
T70201 |
S 16020-2
|
||
S 16020-2 is an olivacine derivative, and DNA topoisomerase II inhibitor endowed with a remarkable antitumor activity against various experimental tumors. | |||
T39047 |
DDR2-IN-1
DDR2-IN-1 |
||
DDR2-IN-1 (Compound 129) is recognized as a highly effective DDR2 inhibitor, displaying an IC50 value of 26 nM. It is a suitable choice for conducting osteoarthritis research. | |||
T36701 | Phosphoramide mustard (cyclohexanamine) | ||
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA damage and elicits the ovarian DNA repair response[1][2]. Phosphoramide mustard cyclohexanamine causes cytotoxicity through forming cross-linked DNA adducts which inhibit DNA strand separation during replication[1].Phosphoramide mustard cyclohexanamine destroys rapidly dividing ce... |