Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01043 |
PHS Protein, Human, Recombinant (His)
4-Alpha-Hydroxy-Tetrahydropterin Dehydratase,Pterin-4-α-Carb... |
Human | E. coli |
Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type ... |