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11

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40771	5-Propargylamino-3'-azidomethyl-dCTP
	5-Propargylamino-3'-azidomethyl-dCTP, is a nucleoside molecule. It finds utility in DNA synthesis and DNA sequencing.
T38546	5-Propargylamino-dCTP
	5-Propargylamino-dCTP, also known as dCTP-PA, is a nucleoside molecule. It can form conjugates with molecular markers, enabling its application in nucleic acid labeling and sequence analysis.
T38526	5-Propargylamino-ddCTP
	5-Propargylamino-ddCTP is a nucleoside molecule utilized in the synthesis of cyanine dye-nucleotide conjugate, which finds application in nucleic acid labeling and sequence analysis.
T63602	ddCTP trisodium
	ddCTP trisodium 是一种核苷类似物，靶向人类免疫缺陷病毒 (HIV) 的逆转录酶，可用于研究艾滋病 (AIDS)。ddCTP trisodium 是一类双脱氧核糖核苷酸 (ddNTPs)，也是一种 DNA 聚合酶链延长抑制剂，能够用于 DNA 测序的研究。
T75376	Biotin-11-dCTP
	Biotin-11-dCTP 是一种用于 DNA 标记的荧光染料。
T40759	ddCTP
	ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing.
T75387	Cy3-dCTP
	Cy3-dCTP为直接标记DNA探针的荧光标记核苷酸，同时作为氰染料标记的三磷酸核苷酸，适用于成像研究。
T41110	EFdA-TP
	EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.
T79743	Caspase-3 activator 1	Pyroptosis	Apoptosis; Immunology/Inflammation
	Caspase-3 activator 1 (compound 4b) 是一种Ru(III)金属复合物，它能够有效抑制胃肿瘤细胞的生长与转移。该化合物通过介导caspase-3的活化而促进GSDME的裂解，产生GSDME-N末端，导致胃肿瘤细胞发生膜穿孔。Caspase-3 activator 1还能诱导焦亡及其引发的免疫应答，并可与地西他滨（DCT）构建成4b-DCT-Lip脂质纳米粒子，用于高效药物递送。
T35649	EFdA-TP tetraammonium
	EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally, EFdA-TP tetraammonium exhibits multiple mechanisms of inhibiting HIV-1 RT[1].
T72461	EFdA-TP tetrasodium	Reverse Transcriptase	Microbiology/Virology
	EFdA-TP tetrasodium作为一种核苷逆转录酶（RT）的高效抑制剂，能够作为立即或延迟链终止剂（ICT或DCT）来抑制RT催化的DNA合成，并且能通过多种机制抑制HIV-1 RT。

化合物

5-Propargylamino-3'-azidomethyl-dCTP

Cat.No: T40771

5-Propargylamino-dCTP

Cat.No: T38546

5-Propargylamino-ddCTP

Cat.No: T38526

ddCTP trisodium

Cat.No: T63602

Biotin-11-dCTP

Cat.No: T75376

Cat.No: T40759

Cat.No: T75387

Cat.No: T41110

Caspase-3 activator 1

Cat.No: T79743

Target: Pyroptosis

EFdA-TP tetraammonium

Cat.No: T35649

EFdA-TP tetrasodium

Cat.No: T72461

Target: Reverse Transcriptase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02751	DCT Protein, Mouse, Recombinant (His & SUMO) TRP2,L-dopachrome Delta-isomerase,TRP-2,TYRP2,L-dopachrome t...	Mouse	E. coli
	Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA). DCT Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 69.7 kDa and the accession number is P29812.
TMPH-01608	DCT Protein, Human, Recombinant (His & Myc & SUMO) DT,TYRP2,Tyrosinase-related protein 2,L-dopachrome Delta-iso...	Human	E. coli
	Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
TMPH-01253	DCTN3 Protein, Human, Recombinant (His & SUMO) DCTN22,Dynactin complex subunit 22 kDa subunit (p22...	Human	E. coli
	Together with dynein may be involved in spindle assembly and cytokinesis. DCTN3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.3 kDa and the accession number is O75935.
TMPH-01252	DCTN1 Protein, Human, Recombinant (His & SUMO) DCTN1,150 kDa dynein-associated polypeptide,Dynacti...	Human	E. coli
	DCTN1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.2 kDa and the accession number is Q14203.

重组蛋白

DCT Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02751

Species: Mouse

Expression System: E. coli

DCT Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01608

Species: Human

Expression System: E. coli

DCTN3 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01253

Species: Human

Expression System: E. coli

DCTN1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01252

Species: Human

Expression System: E. coli

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