Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T15067 |
DBCO-NHS ester
|
Others | Others |
DBCO-NHS ester 是一种 ADC 连接剂,可裂解的 3 单元 PEG,还可以用于合成抗体药物共轭物 (ADC)。 | |||
T15073 |
DBCO-PEG4-NHS ester
|
PROTAC Linker | PROTAC |
DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17791 |
DBCO-PEG3-NHS ester
|
Others | Others |
DBCO-PEG3-NHS ester是一种可降解的 ADC linker,可用于合成抗体偶联活性分子 。 | |||
T15075 |
DBCO-PEG5-NHS ester
|
Others | Others |
DBCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T17807 |
DBCO-PEG8-NHS ester
|
Others | Others |
DBCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17783 |
DBCO-PEG12-NHS ester
|
Others | Others |
DBCO-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17775 |
DBCO-NHS ester 3
|
Others | Others |
DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2]. | |||
T17779 |
DBCO-PEG1-NHS ester
|
Others | Others |
DBCO-PEG1-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T15066 |
DBCO-NHS ester 2
|
Others | Others |
DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1]. | |||
T15065 | DBCO-NHCO-PEG5-NHS ester | Others | Others |
DBCO-NHCO-PEG5-NHS ester is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1]. | |||
T17762 |
DBCO-NHCO-PEG13-NHS ester
|
Others | Others |
DBCO-NHCO-PEG13-NHS ester is a pegylated PROteolysis-TArgeting Chimera (PROTAC) linker, serving as a valuable tool for PROTAC synthesis[1]. | |||
T15064 |
DBCO-NHCO-PEG4-NHS ester
|
Others | Others |
DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T39446 |
PC DBCO-PEG4-NHS ester
PC DBCO-PEG4-NHS ester |
||
PC DBCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17767 |
DBCO-NHCO-PEG2-NHS ester
|
Others | Others |
DBCO-NHCO-PEG2-NHS ester, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1]. | |||
T17757 |
DBCO-NHCO-C4-NHS ester
|
Others | Others |
DBCO-NHCO-C4-NHS ester is an alkyl chain-derived PROTAC linker applicable for PROTACs synthesis[1]. | |||
T15078 |
DBCO-Sulfo-NHS ester sodium
|
Others | Others |
DBCO-Sulfo-NHS ester sodium is a cleavable linker predominantly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T17748 | DBCO-CONH-S-S-NHS ester | Others | Others |
DBCO-CONH-S-S-NHS ester is a disulfide-linked ADC linker employed for the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T17756 |
DBCO-NH-PEG7-C2-NHS ester
|
Others | Others |
DBCO-NH-PEG7-C2-NHS ester is a polyethylene glycol (PEG) derived linker that possesses a terminal DBCO moiety. It functions as an N-hydroxysuccinimide (NHS) ester, making it suitable for the efficient synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T17774 | DBCO-NHCO-S-S-NHS ester | Others | Others |
DBCO-NHCO-S-S-NHS ester is a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T18410 |
N-DBCO-N-bis(PEG2-C2-NHS ester)
|
Others | Others |
N-DBCO-N-bis(PEG2-C2-NHS ester) is a Polyethylene Glycol (PEG) derived linker that finds utility in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. | |||
T29389 |
3-Azidopropionic Acid Sulfo-NHS Ester
|
||
3-Azidopropionic Acid Sulfo-NHS Ester is a water-soluble compound containing an azide group and an NHS ester. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the p | |||
T15057 |
DBCO-acid
|
Others | Others |
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and drug-linker conjugates DBCO-PEG-MMAE[1]. |