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Search Results for " d erythro sphingosine "

15

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T84509	Sphingosine (d15:1) D-erythro-Sphingosine C-15	Others	Others
	Sphingosine (d18:1), an amino alcohol, is chiefly recognized for its 18-carbon unsaturated hydrocarbon chain. Nevertheless, in mammalian tissues, both sphingosine and its variant, dihydrosphingosine, feature hydrocarbon chains ranging from 12 to 26 carbons. Sphingosine (d15:1) represents a naturally rare variant, serving as an internal standard for chromatographic or spectrometric analyses of sphingoid compounds.
T85010	Sphingosine (d16:1) D-erythro-Sphingosine C-16	Others	Others
	Sphingosine (d16:1), an unconventional sphingolipid, is synthesized through enzymatic reactions starting with the condensation of myristoyl-CoA and serine by serine palmitoyltransferase long-chain base subunit 3 (SPTLC3), which shows a preference for myristoyl-CoA. This compound is found in minute quantities in its free form in human plasma and as a component of various plasma sphingolipids, such as sphingosine-1-phosphate, ceramides, sphingomyelins, and in brain cerebrosides, albeit at lower co...
T85161	N,N-dihexyl Sphingosine (d18:1/6:0/6:0) N,N-dihexyl-D-erythro-Sphingosine	Others	Others

T20827	C8-Ceramide N-辛酰基-D-神经鞘氨醇,N-Octanoyl-D-erythro-Sphingosine	Others	Others
	C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides.
T84383	C2 dihydro Ceramide (d18:0/2:0) Cer(d18:0/2:0),N-acetyl-D-erythro-Sphinganine,N-acetyl-dihydro-Sphingosine,Ceramide (d18:0/2:0),N-acetyl-D-erythro-dihydro-Sphingosine	Others	Others

T37436	C12-Ceramide N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine
	C12-Ceramide (C12 Ceramide (d18:1/12:0)) 是一种存在于先兆子痫妇女所生婴儿围绕脐带血管的保护膜的神经酰胺，是 C12 鞘磷脂被酸性鞘磷脂酶（ASM）水解后形成的，可用于评估 A 型或 B 型尼曼-皮克病患者血浆中的 ASM 活性水平。
T85275	C32 Ceramide (d18:1/32:0) Cer(d18:1/32:0),N-dotriacontanoyl-D-erythro-Sphingosine,Ceramide (d18:1/32:0)	Others	Others

T85193	C10 Ceramide (d18:1/10:0) Ceramide (d18:1/10:0),N-decanoyl-D-erythro-Sphingosine,C10 Ceramide,Cer(d18:1/10:0)	Others	Others

T85189	C15 Ceramide (d18:1/15:0) Ceramide (d18:1/15:0),N-pentadecanoyl-D-erythro-Sphingosine,Cer(d18:1/15:0)	Others	Others

T83880	C18 Ceramide-1-phosphate (d18:1/18:0) ammonium Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate	Others	Others
	C18 Ceramide-1-phosphate (d18:1/18:0) 是一种在鼠皮肤中发现的长链ceramide-1-phosphate。它能在0.5至5 µM的浓度范围内促进分离的小鼠骨髓来源的多能间充质细胞和人脐静脉内皮细胞（HUVECs）的迁移。与胰腺癌干细胞相比，CFPAC-1胰管腺癌细胞中C18 Ceramide-1-phosphate (d18:1/18:0)的水平有所增加。在Langendorff分离的灌流小鼠心脏的离体缺血模型中，心肌中C18 ceramide-1-phosphate (d18:1/18:0)的水平有所增加。
T85290	C6 Biotin Ceramide (d18:1/6:0) N-hexanoyl-biotin-D-erythro-Sphingosine,N-C6:0-biotin-D-erythro-Ceramide,Biotin Cer(d18:1/6:0),Biotin Ceramide (d18:1/6:0),C6 Ceramide-biotin	Others	Others

T85289	C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) ((±)-2'-hydroxy) Cer(d18:1/18:0),((±)-2'-hydroxy) Ceramide (d18:1/18:0),18:0 (2R/S-OH)-Ceramide,N-(2'-(R,S)-hydroxystearoyl)-D-erythro-Sphingosine	Others	Others

T85284	C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0) N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine,2'(S)-hydroxy Cer(d18:1/16:0),2'-hydroxy C16-Ceramide,(2'(S)-hydroxy) Ceramide (d18:1/16:0),16:0 (2S-OH)-Ceramide	Others	Others

T38946	C8 Dihydroceramide C8 Dihydroceramide	Others	Others
	C8 Dihydroceramide acts as a negative control for C8 Ceramide, a cell-permeable analog of natural ceramides. C8 Ceramide, also known as N-Octanoyl-D-erythro-sphingosine, exhibits potent chemotherapeutic properties and anti-proliferation effects. Additionally, it stimulates dendritic cells to enhance T cell responses during viral infections. In vitro studies have also shown that C8 Ceramide induces a slight activation of protein kinase (PKC) [4].
T35781	Sphinganine (d20:0) Sphinganine (d20:0)	Others	Others
	Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well ...

化合物

Sphingosine (d15:1)

Cat.No: T84509

Synonym: D-erythro-Sphingosine C-15

Target: Others

Sphingosine (d16:1)

Cat.No: T85010

Synonym: D-erythro-Sphingosine C-16

Target: Others

N,N-dihexyl Sphingosine (d18:1/6:0/6:0)

Cat.No: T85161

Synonym: N,N-dihexyl-D-erythro-Sphingosine

Target: Others

Cat.No: T20827

Synonym: N-辛酰基-D-神经鞘氨醇,N-Octanoyl-D-erythro-Sphingosine

Target: Others

C2 dihydro Ceramide (d18:0/2:0)

Cat.No: T84383

Synonym: Cer(d18:0/2:0),N-acetyl-D-erythro-Sphinganine,N-acetyl-dihydro-Sphingosine,Ceramide (d18:0/2:0),N-acetyl-D-erythro-dihydro-Sphingosine

Target: Others

Cat.No: T37436

Synonym: N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine

C32 Ceramide (d18:1/32:0)

Cat.No: T85275

Synonym: Cer(d18:1/32:0),N-dotriacontanoyl-D-erythro-Sphingosine,Ceramide (d18:1/32:0)

Target: Others

C10 Ceramide (d18:1/10:0)

Cat.No: T85193

Synonym: Ceramide (d18:1/10:0),N-decanoyl-D-erythro-Sphingosine,C10 Ceramide,Cer(d18:1/10:0)

Target: Others

C15 Ceramide (d18:1/15:0)

Cat.No: T85189

Synonym: Ceramide (d18:1/15:0),N-pentadecanoyl-D-erythro-Sphingosine,Cer(d18:1/15:0)

Target: Others

C18 Ceramide-1-phosphate (d18:1/18:0) ammonium

Cat.No: T83880

Synonym: Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate

Target: Others

C6 Biotin Ceramide (d18:1/6:0)

Cat.No: T85290

Synonym: N-hexanoyl-biotin-D-erythro-Sphingosine,N-C6:0-biotin-D-erythro-Ceramide,Biotin Cer(d18:1/6:0),Biotin Ceramide (d18:1/6:0),C6 Ceramide-biotin

Target: Others

C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0)

Cat.No: T85289

Synonym: ((±)-2'-hydroxy) Cer(d18:1/18:0),((±)-2'-hydroxy) Ceramide (d18:1/18:0),18:0 (2R/S-OH)-Ceramide,N-(2'-(R,S)-hydroxystearoyl)-D-erythro-Sphingosine

Target: Others

C16 (2'(S)-hydroxy) Ceramide (d18:1/16:0)

Cat.No: T85284

Synonym: N-(2'-(S)-hydroxypalmitoyl)-D-erythro-Sphingosine,2'(S)-hydroxy Cer(d18:1/16:0),2'-hydroxy C16-Ceramide,(2'(S)-hydroxy) Ceramide (d18:1/16:0),16:0 (2S-OH)-Ceramide

Target: Others

C8 Dihydroceramide

Cat.No: T38946

Synonym: C8 Dihydroceramide

Target: Others

Sphinganine (d20:0)

Cat.No: T35781

Synonym: Sphinganine (d20:0)

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5891	D-ERYTHRO-SPHINGOSINE trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine,鞘氨醇,D-鞘氨醇	Phosphatase; Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	D-erythro-Sphingosine (trans-4-Sphingenine) 是一种非常有效的p32激酶活化剂，EC50为 8 μM。它也是一种PP2A 激活剂，抑制蛋白激酶 C (PKC)。
T72100	D-erythro-Sphingosine hydrochloride Erythrosphingosine hydrochloride,trans-4-Sphingenine hydrochloride,erythro-C18-Sphingosine hydrochloride,Erythrosphingosine hydrochloride ; erythro-C18-Sphingosine hydrochloride ; trans-4-Sphingenine hydrochloride	Others	Others
	D-erythro-Sphingosine (Erythrosphingosine) hydrochloride 是一种特异性 TRPM3活化剂。D-erythro-Sphingosine 还诱导视网膜母细胞瘤蛋白 (retinoblastoma protein) 去磷酸化。

天然产物

D-ERYTHRO-SPHINGOSINE

Cat.No: T5891

Synonym: trans-4-Sphingenine,erythro-C18-Sphingosine,Erythrosphingosine,鞘氨醇,D-鞘氨醇

Target: Phosphatase, Endogenous Metabolite, PKC

D-erythro-Sphingosine hydrochloride

Cat.No: T72100

Synonym: Erythrosphingosine hydrochloride,trans-4-Sphingenine hydrochloride,erythro-C18-Sphingosine hydrochloride,Erythrosphingosine hydrochloride ; erythro-C18-Sphingosine hydrochloride ; trans-4-Sphingenine hydrochloride

Target: Others

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