Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7495 |
Hexa-D-arginine
|
Others | Others |
Hexa-D-arginine 是稳定的furin 抑制剂,能够作用于 furin (Ki:106 nM)、PACE4 (Ki:580 nM)、PC1 (Ki:13.2 nM)。它在体外和体内均可阻断假单胞菌外毒素 A 和炭疽毒素的毒性。 | |||
T9537 |
N'-Nitro-D-arginine
N'-Nitro-D-arginine,H-D-Arg(NO2)-OH,(R)-2-Amino-5-(3-nitroguanidino)pentanoic acid,N'-硝基-D-精氨酸 |
Others | Others |
N'-Nitro-D-arginine (N'-Nitro-D-arginine) 是一种砌块。 | |||
T41330 |
D-Arginine
|
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D-Arginine 在生命科学相关研究中具有广泛的应用。 | |||
TP1160 |
Hexa-D-arginine TFA
Furin Inhibitor II TFA |
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Hexa-D-arginine TFA (Furin Inhibitor II TFA) is an inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively). | |||
T83502 |
[Deamino-4-valine, 8-D-arginine]-Vasopressin
dVDAVP |
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[Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP)为一种抗利尿药,具有高效性、特异性以及延长的药效特点。 | |||
T65254 |
N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine
|
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N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65254,CAS号为 50913-12-7。 | |||
T36719 |
D-NAME (hydrochloride)
|
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N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester . D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints. D-NAME (3-10 µg/mouse) had no effect on no... | |||
T40884 |
SKF 100398
d(CH2)5Tyr(Et)VAVP |
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SKF 100398, also known as d(CH2)5Tyr(Et)VAVP, is a particular analog of arginine vasopressin (AVP). It acts as a specific antagonist, specifically targeting the antidiuretic effect caused by both exogenous and endogenous AVP. | |||
T23177 |
PPACK Dihydrochloride (71142-71-7 free base)
PPACK Dihydrochloride |
Others | Others |
PPACK Dihydrochloride is the dihydrochloride form of its active component PPACK (D-Phenylalanyl-L-prolyl-L-arginine chloromethyl ketone), a potent, selective, and irreversible inhibitor of thrombin that inhibits human α-thrombin with inhibition constant ( | |||
T82261 |
Grb2 SH2 domain inhibitor 1
|
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Grb2 SH2 domain inhibitor 1是构象受限环细胞穿透肽(CPP),主要用作环状肽基抑制剂,包含特定d-Pro-l-Pro基序环(AFΦrpPRRFQ),其中Φ为l-萘基丙氨酸,r为d-精氨酸,p为d-脯氨酸。 | |||
T77994 |
Grb2 SH2 domain inhibitor 1 TFA
|
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Grb2 SH2 domain inhibitor 1 TFA 是构象受限的环细胞穿透肽(CPP),含有d-Pro-l-Pro基序环(AFΦrpPRRFQ),Φ为l-萘基丙氨酸,r为d-精氨酸,p为d-脯氨酸,主要用作环状肽基抑制剂。 | |||
T80228 |
r8-Gly-Noxa A BH3
|
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r8-Gly-Noxa A BH3 是一种源自 Noxa A BH3 (死亡结构域) 结构域氨基酸残基 17 至 36 的具有生物活性的细胞渗透性肽。该肽在氨基末端通过添加 8 个 D-精氨酸残基和一个甘氨酸接头残基而进行了修饰。 | |||
T80114 |
FA-Ala-Arg
|
Endogenous Metabolite | Metabolism |
FA-Ala-Arg是一种携带呋喃丙烯酰基的二肽,它能够分解产生精氨酸,并因此提高精氨酸水平,后者可转化为一氧化氮(NO)。该化合物还可增强MCF-7细胞产生NO的能力,并在催乳素(PRL)处理下提升细胞存活率,其中PRL会调节CPD mRNA的表达。 | |||
T83501 |
[Deamino-Pen1,Val4,D-Arg8]-vasopressin
|
Vasopressin Receptor | GPCR/G Protein |
"[Deamino-Pen1,Val4,D-Arg8]-vasopressin (AVP-A)是一种作用于精氨酸血管加压素(AVP)的拮抗剂,它能有效地降低大鼠血浆中的醛固酮浓度。本化合物主要应用于研究大鼠肾上腺球状带的生长及其类固醇生成作用。" | |||
T80226 |
r8 Bid BH3
|
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r8 Bid BH3是一种促凋亡的生物活性肽,属于"BCL-2家族"中的“仅具BH3功能域”的亚群,对Bcl-2表达的人类白血病细胞系显示出致死性。作为Bcl-2拮抗剂,它具备治疗癌症的潜力。此外,多聚-D-精氨酸(d-异构体,标记为rrrrrrrr)被融合到Bid BH3肽上,以提高其被细胞摄取的能力。 |