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Cat. No. | Product Name | Target | Signaling Pathways |
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T11466 |
GSK-2793660
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Others | Others |
GSK-2793660 是一种具有口服活性并且不可逆的组织蛋白酶 C (Cathepsin C;CTSC) 抑制剂。GSK-2793660 是一种生物活性肽,可用于支气管扩张的研究。 | |||
T27468 |
GSK2793660 HCl
GSK-2793660,GSK2793660,GSK 2793660 |
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GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor. | |||
T70381 |
GSK2793660 free base
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GSK-2793660 is a cathepsin C inhibitor that may be useful in the treatment of cystic fibrosis, noncystic fibrosis bronchiectasis, ANCA-associated vasculitis and bronchiectasis. |
Cat. No. | Product Name | Species | Expression System |
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TMPH-02628 |
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Dipeptidyl transferase,Dipeptidyl peptidase I,Cathepsin J,DP... |
Mouse | E. coli |
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function. | |||
TMPY-00732 |
Cathepsin C Protein, Human, Recombinant (His)
DPP-I,PLS,JP,cathepsin C,CPPI,DPPI,PDON1,PALS,DPP1,JPD,HMS |
Human | HEK293 Cells |
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c... |