Cat. No. | Product Name | Target | Signaling Pathways |
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T40367 |
Combretastatin A-1 phosphate tetrasodium
Combretastatin A-1 phosphate tetrasodium,OXi-4503 tetrasodium |
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Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a prodrug of Combretastatin A-1, is a tubulin-binding microtubule polymerization inhibitor that targets the colchicine-binding site. By inducing tubulin depolymerization, Combretastatin A-1 phosphate tetrasodium inhibits the Wnt/β-catenin pathway and leads to the deactivation of AKT. It possesses both anti-tumor and anti-vascular properties. |