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Search Results for " chloramphenicol "

14

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T20525	Chloramphenicol palmitate	Antibacterial; Antibiotic	Microbiology/Virology
	Chloramphenicol palmitate 是一种广谱抗生素，对革兰氏阳性和革兰氏阴性细菌具有活性。 Chloramphenicol palmitate 可用于在含有氯霉素抗性基因的转化细胞中作为细菌选择剂的研究。
T24401	L-erythro-Chloramphenicol L(+)-erythro-Chloramphenicol
	L-erythro-Chloramphenicol functions as a potent inhibitor of electron transport.
T25239	Chloramphenicol stearate Eusynthomycin,Chloramphenicol monostearate,Madomicetina
	Chloramphenicol stearate is an antibiotic useful for the therapy of numbers of bacterial infections. This includes an eye ointment to treat conjunctivitis.
T23985	Dextramycine Dextramycin,(+)-Chloramphenicol,Dextromycetin,L-threo-Chloramphenicol
	Dextramycine is an optic isomer of chloramphenicol.
T74079	m-Chloramphenicol
	m-Chloramphenicol (m-threo-Chloramphenicol) 是 Chloramphenicol 的一种杂质。Chloramphenicol 是一种广谱抗生素，是细菌蛋白质生物合成的有效抑制剂。
T14391	Azidamfenicol	Antibacterial; Antibiotic	Microbiology/Virology
	Azidamfenicol 抑制核糖体肽基转移酶，Ki 为 22 µM。Azidamfenicol 是一种广谱氯霉素类抗生素。
T1550	Thiamphenicol 甲砜霉素,Dextrosulphenidol,Thiophenicol	Antibacterial; Antibiotic	Microbiology/Virology
	Thiamphenicol (Dextrosulphenidol) 是 Chloramphenicol 的甲基磺酰基衍生物，是一种广谱抗菌类抗生素。它与 50S 核糖体亚基结合，抑制蛋白质合成并具有抑菌作用，特别针对革兰氏阴性，革兰氏阳性需氧和厌氧菌。
T36020	Florfenicol amine (hydrochloride)
	Florfenicol amine is a major metabolite of the antibiotic florfenicol, a fluorinated derivative of chloramphenicol that is commonly used in veterinary medicine. The pharmacokinetics of florfenicol and florfenicol amine are commonly studied in edible tissues from domestic animals.
T36849	Corynecin V
	Corynecin V is a chloramphenicol-like bacterial metabolite originally isolated from Corynebacterium.
T27394	Furalazine Furalazinum,Panfuran,Nifuralazinum,NFT
	Furalazine is an antimicrobial agent. Furalazine was more effective in reducing the duration of positive stool culture than chloramphenicol. It may be potentially used in the treatment of cholera.
T38334	Corynecin III
	Corynecin III is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It inhibits the growth of Gram-positive and Gram-negative bacteria, including S. faecalis, S. aureus, B. subtilis, E. coli, P. aeruginosa, P. vulgaris, S. sonnei, S. typhosa, and K. pneumoniae (MICs = 2.6-83 μg/ml).
T38333	Corynecin I
	Corynecin I is a chloramphenicol-like antibiotic originally isolated from Corynebacterium. It is active against Gram-positive and Gram-negative bacteria with MIC values of 5.2-83 μg/ml for S. sonnei, P. vulgaris, K. pneumoniae, and S. aureus among others.
T35651	Bromamphenicol
	Bromamphenicol is a dibrominated derivative of the antibiotic chloramphenicol. It inhibits rat liver mitochondrial and E. coli protein synthesis by 90.6 and 98.8%, respectively, when used at a concentration of 93 μM, and inhibits DNA synthesis in human lymphoblastoid cells by 83% at 1 mM. Bromamphenicol can also bind to the major adhesin subunit DraE from E. coli.
T80385	K11
	K11是一种具有针对MDR/XDR K. pneumoniae活性的抗菌肽（MIC: 8-512 μg/mL），能够抑制该细菌的生物膜的形成。它还可以与多种抗生素（如Chloramphenicol、Meropenem、Rifampicin等）产生协同效应，增强对耐药K. pneumoniae的抗性。此外，K11显示出良好的高温稳定性和在宽pH范围内的稳定性。

化合物

Chloramphenicol palmitate

Cat.No: T20525

Target: Antibacterial, Antibiotic

L-erythro-Chloramphenicol

Cat.No: T24401

Synonym: L(+)-erythro-Chloramphenicol

Chloramphenicol stearate

Cat.No: T25239

Synonym: Eusynthomycin,Chloramphenicol monostearate,Madomicetina

Cat.No: T23985

Synonym: Dextramycin,(+)-Chloramphenicol,Dextromycetin,L-threo-Chloramphenicol

m-Chloramphenicol

Cat.No: T74079

Cat.No: T14391

Target: Antibacterial, Antibiotic

Cat.No: T1550

Synonym: 甲砜霉素,Dextrosulphenidol,Thiophenicol

Target: Antibacterial, Antibiotic

Florfenicol amine (hydrochloride)

Cat.No: T36020

Cat.No: T36849

Cat.No: T27394

Synonym: Furalazinum,Panfuran,Nifuralazinum,NFT

Cat.No: T38334

Cat.No: T38333

Cat.No: T35651

Cat.No: T80385

Cat. No.	Product Name	Target	Signaling Pathways
T1205	Chloramphenicol Chlornitromycin,Levomycetin,Chloromycetin,氯霉素	ribosome; HIF/HIF Prolyl-Hydroxylase; Antibacterial; Antibiotic	Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Chloramphenicol (Chloromycetin) 是一种广谱抗生素，有效抑制细菌蛋白质生物合成。它主要作用于细菌 70S 核糖体的 50S 亚基，对肽基转移酶有活性，抑制肽键的形成。
T8258	Chloramphenicol succinate sodium Chloramphenicol sodium succinate,琥珀酸钠氯霉素,氯霉素琥珀酸钠	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Chloramphenicol succinate sodium 是 Chloramphenicol 的前药，具有血液学毒性。它是琥珀酸脱氢酶的竞争底物和抑制剂。
T25240	Chloramphenicol succinate Paraxin succinate,Kemicetine succinate,CPSA
	Chloramphenicol succinate is an inactive precursor of chloramphenicol. It is used for parenteral administration of chloramphenicol.
T11842	Levomecol	Others	Others
	Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthesis by blocking peptidyl transferase.

天然产物

Chloramphenicol

Cat.No: T1205

Synonym: Chlornitromycin,Levomycetin,Chloromycetin,氯霉素

Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Chloramphenicol succinate sodium

Cat.No: T8258

Synonym: Chloramphenicol sodium succinate,琥珀酸钠氯霉素,氯霉素琥珀酸钠

Target: Others, Antibacterial, Antibiotic

Chloramphenicol succinate

Cat.No: T25240

Synonym: Paraxin succinate,Kemicetine succinate,CPSA

Cat.No: T11842

Target: Others

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