9
9
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T22288 |
(1E)-CFI-400437 dihydrochloride
CFI-400437 dihydrochloride |
PLK | Cell Cycle/Checkpoint |
(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) 是一种选择性和有效的 polo 样激酶 4 (PLK4) 抑制剂,IC50为 0.6 nM。它还抑制 Aurora A、 Aurora B、 KDR 和 FLT-3,IC50分别为 0.37、0.21、0.48 和 0.18 μM,具有抗增殖活性。 | |||
T22289 |
CFI-402257
|
Kinesin | Cytoskeletal Signaling |
CFI-402257 是 Mps1/TTK 激酶的选择性抑制剂(Mps1 Ki = 0.09 nM;EC50 = 6.5 nM),可用于肝细胞癌疾病的研究。 | |||
T7384 |
Ocifisertib(CFI-400945 free base)
|
PLK | Cell Cycle/Checkpoint |
CFI-400945 是一种有效的、选择性的、具有口服活性的 polo 样激酶 4(PLK4;Ki 值为 0.26 nM)的抑制剂。 | |||
T30804 |
CFI-401870
CFI 401870 |
||
CFI-401870 is an orally bioavailable potent tyrosine threonine kinase (TTK) inhibitor. | |||
T70940 |
CFI-400936
|
||
CFI-400936 is a potent and selective TTK inhibitor with potential anticancer activity. This potent inhibitor of TTK (IC50=3.6nM) demonstrated good activity in cell based assay and selectivity against a panel of human kinases. | |||
T30805 |
CFI-401980
|
||
CFI-401980 is a potent and selective, novel class of TTK inhibitor. | |||
T22645 |
CFI-400945
|
Others | Others |
CFI-400945 is an orally active, potent, and selective inhibitor of polo-like kinase 4. | |||
T63318 |
CFI-400437
|
||
CFI-400437 是一种ATP 竞争性的PLK4抑制剂 (IC50: 0.6 nM),是一种吲哚醌衍生物。 | |||
T70938 |
SN00799639
|
||
SN00799639, also known as SN639, is a potent inhibitor of the motility and development of parasitic larvae of Haemonchus contortus, a blood-feeding parasitic nematode of major economic importance in ruminants. SN639 displayed lower potency, with IC50 values of 8.4 μM (xL3 motility) and 0.29 μM (L4 development). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06976 |
CFI Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.75 kDa and the accession number is Q61129. | |||
TMPH-03273 |
Complement factor I Protein, Rat, Recombinant (His & Myc)
If,Complement factor I,Cfi,C3B/C4B inactivator |
Rat | Baculovirus Insect Cells |
Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q9WUW3. | |||
TMPK-01023 |
Complement factor I Protein, Mouse, Recombinant (His)
FIC3b-INA,I factor (complement),IF,C3B/C4B inactivator,C3BIN... |
Mouse | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129. | |||
TMPK-00776 |
Complement factor I Protein, Human, Recombinant (His)
FIC3b-INA,KAF,IF,CFI,I factor (complement),EC:3.4.2... |
Human | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.58 kDa and the accession number is P05156. | |||
TMPY-06207 |
Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His)
|
HMPV | HEK293 Cells |
Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0320/2010/A) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is X4XYT2. | |||
TMPY-06206 |
Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His)
|
HMPV | HEK293 Cells |
Human metapneumovirus (strain HMPV/Homo sapiens/PER/CFI0466/2010/B) glycoprotein G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.6 kDa and the accession number is X4Y8Q3. | |||
TMPH-02845 |
Properdin Protein, Mouse, Recombinant (His & Myc)
|
Mouse | HEK293 Cells |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). | |||
TMPH-02844 |
Properdin Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b). | |||
TMPH-03038 |
Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
Cobra venom factor,Complement C3 homolog,CVFk,CVF |
Naja kaouthia | E. coli |
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re... |