Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14931 | Cerivastatin | Others | Others |
Cerivastatin is a highly potent, well-tolerated, and orally active HMG-CoA reductase inhibitor (Ki: 1.3 nM/L). Cerivastatin also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition with anti-cancer effect. Cerivastatin r | |||
T70419 | Cerivastatin lactone | ||
Cerivastatin lactone is a metabolite of a competitive inhibitor of HMG-CoA reductase, Cerivastatin. Cerivastatin lactone shows inhibitory effects on CYP3A4/5 activity. | |||
T10767 |
Cerivastatin sodium
|
HMG-CoA Reductase | Metabolism |
Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent and orally active HMG-CoA reductase inhibitor (Ki: 1.3 nM). It also inhibits the proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition. |