Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T78840 |
Carbonic anhydrase inhibitor 15
|
Carbonic Anhydrase | Metabolism |
Carbonic anhydrase inhibitor15 (Compound 8) 是具有Ki值为8.5 nM对hCA II的碳酸酐酶抑制剂,同时展现出镇痛效应。 | |||
T60408 | hCA VB-IN-1 | ||
hCA VB-IN-1 (compound 15) 是一种hCA VB(碳酸酐酶 VB)的强效选择性抑制剂,KI 值为 515.7 nM。 | |||
T73029 |
hCAIX-IN-15
|
Carbonic Anhydrase | Metabolism |
hCAIX-IN-15,一种高效hCA IX抑制剂,Ki值仅为38.8 nM,展现出优秀的广谱抗癌活性,适用于癌症研究。 | |||
T79451 | WES-1 | Carbonic Anhydrase | Metabolism |
WES-1(Compound 8g)是一种针对碳酸酐酶IX的抑制剂,其抑制常数(Ki)为55.9 μM。该化合物对包括白血病细胞系(K-562、MOLT-4)、非小细胞肺癌(NCI-H460)、结肠癌(HCT 116、HCT-15)以及黑色素瘤(LOX IMVI)在内的多种癌细胞表现出抗增殖效果。 | |||
T37847 |
Zonisamide-13C2,15N
Zonisamide-13C2,15N |
||
Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium... |