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Cat. No.	Product Name	Target	Signaling Pathways
T72122	Carbonic anhydrase inhibitor 12	Carbonic Anhydrase	Metabolism
	碳酸酐酶抑制剂12是针对CA II具有高效抑制作用的化合物，其Kis值仅为1.72 nM，对CA I亦表现出有效抑制（Kis为271 nM）。此外，该化合物在多种肿瘤细胞系中显示出显著的抗癌活性。
T8611	2,3-dihydro-1H-indene-5-sulfonamide	Carbonic Anhydrase	Metabolism
	2,3-dihydro-1H-indene-5-sulfonamide 是碳酸酐酶 12（人）抑制剂。
T35840	4-Amino-6-chloro-1,3-benzenedisulfonamide
	4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3References1. Nishimori, I., Vullo, D., Minakuchi, T., et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies ...
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...