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Search Results for " ctsk "

2

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T64159	Cathepsin K inhibitor 2
	Cathepsin K inhibitor 2 是一种 cathepsin K 的有效抑制剂。其中 Cathepsin K (Cat K) 是一种半胱氨酸蛋白酶，在 CTSK 基因调控下表达，与骨质疏松症密切相关，能够水解胶原蛋白。Cathepsin K inhibitor 2 对骨关节炎表现出研究潜力。
T81171	SH491
	SH491（Compound 33）是一款抗骨质疏松药物。该化合物能够抑制RANKL诱导的骨髓源性单核细胞（BMM）分化为破骨细胞（IC50: 11.8 nM）。同时，SH491降低了破骨细胞形成的相关标记基因（TRAP、CTSK、MMP-9和ATPase v0d2）以及相应蛋白（TRAP、CTSK、MMP-9）的表达。

化合物

Cathepsin K inhibitor 2

Cat.No: T64159

Cat.No: T81171

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03262	Cathepsin K Protein, Rat, Recombinant (His) CTSO,CTSO2,Cathepsin O2,Cathepsin X,Cathepsin O,CTSK	Rat	E. coli
	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen.
TMPH-02565	Cathepsin K Protein, Mouse, Recombinant (His) Cathepsin O,Cathepsin K,CTSK,Cathepsin O2,CTSO2,Cat...	Mouse	E. coli
	Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Cathepsin K Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.4 kDa and the accession number is P...
TMPH-01061	Cathepsin K Protein, Human, Recombinant (His) CTSO2,Cathepsin X,Cathepsin O2,CTSK,Cathepsin O,Cat...	Human	E. coli
	Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Cathepsin K Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pre...

重组蛋白

Cathepsin K Protein, Rat, Recombinant (His)

Cat.No: TMPH-03262

Species: Rat

Expression System: E. coli

Cathepsin K Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02565

Species: Mouse

Expression System: E. coli

Cathepsin K Protein, Human, Recombinant (His)

Cat.No: TMPH-01061

Species: Human

Expression System: E. coli

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