Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10888 |
CRT0066854 hydrochloride
|
ROCK; PKC | Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Stem Cells |
CRT0066854 hydrochloride 是一种强效选择性非典型 PKCs 抑制剂。CRT0066854 hydrochloride 抑制 PKCι,PKCζ 和 ROCK-II 的 IC50 的值分别为 132nM,639 nM 和 620 nM。 | |||
T27089 |
CRT0066854
CRT0066854 HCl,CRT-0066854 HCl,CRT 0066854,CRT-0066854 |
||
CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids. |