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Cat. No.	Product Name	Target	Signaling Pathways
T71262	AZD-8418
	AZD-8418 is an mGlu2 receptor positive allosteric modulators that attenuates nicotine-taking and nicotine-seeking behavior. Acute treatment with AZD8418 (0.37, 1.12, 3.73, 7.46, and 14.92 mg/kg) and AZD8529 (1.75, 5.83, 17.5, and 58.3 mg/kg) deceased nicotine self-administration and had no effect on food-maintained responding. Chronic treatment with AZD8418 attenuated nicotine self-administration, but tolerance to this effect developed quickly. The inhibition of nicotine self-administration by c...
T17036	Tenidap CP-66248	Lipoxygenase	Metabolism
	Tenidap (CP-66248) 是选择性的环氧合酶抑制剂，有抗炎和抗风湿活性，抑制 COX-1 和COX-2 。Tenidap 是一种特异性的 SLC26A3 抑制剂，在颞叶癫痫的毛果芸香碱大鼠模型中具有神经保护作用，可用研究神经系统疾病。