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Cat. No. Product Name Target Signaling Pathways
T79130 COX-2-IN-32

NF-κB NF-κB
COX-2-IN-32(Compound 2f)为一种抑制iNOS和COX-2的化合物,能够降低NF-κB表达,并抑制LPS诱导的RAW264.7巨噬细胞中NO产生,显示出抗炎活性(IC50: 11.2 μM)。
T37374 URB754

URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. There is evidence that the MAGL inhibitory activity of URB754 may be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial preparations. URB754 inhibits rat brain fa...

化合物

COX-2-IN-32
Cat.No: T79130
Synonym:
Target: NF-κB
URB754
Cat.No: T37374
Synonym:
Target:
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