Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00553 |
ADAM9 Protein, Cynomolgus, Recombinant (His)
Adam9,CORD9,mKIAA0021,Meltrin-γ,M... |
Cynomolgus | HEK293 Cells |
A disintegrin and metalloproteinase 9 (ADAM9) is a member of the transmembrane ADAM family. It is expressed in different types of solid cancer and promotes tumor invasiveness. ADAM9 may be a prognostic marker for vestibular schwannomas (VS), and ADAM9 inhibition might have the potential as a systemic approach for the treatment of VS. | |||
TMPY-02404 |
ADAM9 Protein, Mouse, Recombinant (His)
mKIAA0021,AU020942,ADAM metallopeptidase domain |
Mouse | HEK293 Cells |
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential t... | |||
TMPY-01212 |
ADAM12 Protein, Human, Recombinant (His)
ADAM metallopeptidase domain 12,MLTNA,MCMP,CAR10,MLTN,MCMPMl... |
Human | HEK293 Cells |
The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities. Human ADAM12, which is implicated in diseases such as cancer, is expressed in two splice forms, the transmembrane ADAM12-L and the shorter and soluble ADAM12-S. ADAM12, also known as and Meltrin alpha, is a member of the ADAM protein family, which contains one disintegrin domain, one EGF-like domain and one peptidase M12B domain. ADAM12 is synthes... |