Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01121 |
COL4A3 Protein, Human, Recombinant (His)
Goodpasture antigen,COL4A3,Collag... |
Human | E. coli |
COL4A3 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02591 |
COL4A3 Protein, Mouse, Recombinant (His & Myc)
Goodpasture antigen,Collagen alpha-3(IV) chain,... |
Mouse | E. coli |
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. | |||
TMPY-03272 |
COL4A3 Protein, Rat, Recombinant (hFc)
collagen, type IV, α3 (Goodpasture antigen),col... |
Rat | HEK293 Cells |
COL4A3 is a major structural component of basement membranes. It is composed of 3 alpha subunits, which are encoded by 6 different genes, alpha 1 through alpha 6. Each of these alpha subunits can form a triple helix structure with 2 other subunits to form COL4A3. Autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli can cause goodpasture syndrome. COL4A3 is also linked to an autosomal recessive form of alport syndrome. COL4A3 is organized in a he... | |||
TMPY-03266 |
COL4A3BP Protein, Human, Recombinant (His & GST)
CERTL,GPBP,collagen, type IV, alpha 3 (Goodpasture ... |
Human | Baculovirus Insect Cells |
COL4A3BP is a member of the StarD2 subfamily. It contains a pleckstrin homology domain at its amino terminus and a START domain towards the end of the molecule. COL4A3BP has a lipid-binding domain that mediates intracellular trafficking of ceramide in a non-vesicular manner. One isoform of COL4A3BP is also involved in ceramide intracellular transport. COL4A3BP specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen, known as t... | |||
TMPK-00113 |
Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc)
APCS,MGC88159,SAP,Pentraxin 2,PTX2 |
Mouse | HEK293 Cells |
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc) ... | |||
TMPK-00765 |
Pentraxin 2/SAP Protein, Human, Recombinant (hFc)
PTX2,SAP,Pentraxin 2,MGC88159,APCS |
Human | HEK293 Cells |
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human PTX-2 (rhPTX-2) retards progression of chronic kidney disease in Col4a3 mutant mice with Alport syndrome, reducing blood markers of kidney failure, enhancing lifespan by 20%, and improving histological signs of disease. diseases. Pentraxin 2/SAP Protein, Human, Recombinant (hFc) ... |