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5

抑制剂 & 化合物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40075	PROTAC BRD4 Degrader-13 PROTAC BRD4 Degrader-13
	PROTAC BRD4 Degrader-13 (compound 9d) is a bioactive compound that functions as a proteolysis targeting chimera (PROTAC), linking ligands for von Hippel-Lindau and BRD4 proteins. In the context of PC3 prostate cancer cells, this compound effectively degrades the BRD4 protein through conjugation with STEAP1 and CLL1 antibodies. The degradation of BRD4 protein is achieved with remarkable potency, exhibiting a DC 50 of 0.025 nM and 6.0 nM when combined with STEAP1 and CLL1 antibodies, respectively.
T40073	PROTAC BRD4 Degrader-10 PROTAC BRD4 Degrader-10
	PROTAC BRD4 Degrader-10, also known as compound 8b, is a dual ligand-based PROTAC that combines ligands for von Hippel-Lindau and BRD4. To degrade the BRD4 protein in PC3 prostate cancer cells, PROTAC BRD4 Degrader-10 can be conjugated with STEAP1 and CLL1 antibodies, with respective DC 50 values of 1.3 nM and 18 nM.
T40072	PROTAC BRD4 Degrader-9 PROTAC BRD4 Degrader-9
	PROTAC BRD4 Degrader-9 (compound 8a) is a novel chemical compound consisting of ligands for von Hippel-Lindau and BRD4, connected by a PROTAC moiety. This compound can effectively degrade the BRD4 protein in PC3 prostate cancer cells. When conjugated with STEAP1 and CLL1 antibodies, PROTAC BRD4 Degrader-9 exhibits potent activity, with respective DC50 values of 0.86 nM and 7.6 nM.
T74124	PROTAC BRD4 Degrader-11
	PROTACBRD4Degrader-11 (compound 9a) 是一种有效的由von Hippel-Lindau 配体和BRD4配体相连的PROTAC。PROTACBRD4Degrader-11 可与 STEAP1 和 CLL1 抗体偶联从而降解 PC3 前列腺癌细胞中的BRD4蛋白，DC50值分别为 0.23 nM 和 0.38 nM。
T74125	PROTAC BRD4 Degrader-12
	PROTACBRD4Degrader-12 (compound 9c) 是一种由 von Hippel-Lindau 配体和 BRD4配体相连的 PROTAC。PROTACBRD4Degrader-12 可与 STEAP1 和 CLL1 抗体偶联从而降解 PC3 前列腺癌细胞中的 BRD4蛋白，DC50值分别为 0.39 nM 和 0.24 nM。

化合物

PROTAC BRD4 Degrader-13

Cat.No: T40075

Synonym: PROTAC BRD4 Degrader-13

PROTAC BRD4 Degrader-10

Cat.No: T40073

Synonym: PROTAC BRD4 Degrader-10

PROTAC BRD4 Degrader-9

Cat.No: T40072

Synonym: PROTAC BRD4 Degrader-9

PROTAC BRD4 Degrader-11

Cat.No: T74124

PROTAC BRD4 Degrader-12

Cat.No: T74125

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02092	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) HECL,CLL-1,CD303,PRO34150,DCAL-2,...	Human	HEK293 Cells
	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41~45 kDa and the accession number is EAW96132.1.
TMPK-01004	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc) DCAL2,HECL,DCAL-2,DLEC,CLECSF11,CLEC1<...	Human	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hF...
TMPK-01003	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Biotinylated DCAL2,CD371,CLEC12A,CLL-1	Human	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Bi...
TMPK-00995	CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, His) HECL,CLL1,CD371,CLL-...	Mouse	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, Hi...
TMPK-00548	CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His) CD371,HECL,CLECSF11,CLEC1	Cynomolgus	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His) is ...
TMPK-01005	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled DCAL-2,HECL,CLL-1,CLECSF7,CD371,C...	Human	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-La...
TMPK-01002	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated HECL,DCAL-2,CD303,CLECSF7,DCAL2,CLECSF11,<...	Human	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), B...
TMPK-01006	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His) CLECSF7,CLL-1,PRO34150,CLL	Human	HEK293 Cells
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML. CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, Hi...
TMPY-06866	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc) CLECSF11,MICL,CLECSF7,DLEC,C-type lectin d...	Human	HEK293 Cells
	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.38 kDa and the accession number is EAW96132.1.
TMPY-06881	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (Avi & Fc), Biotinylated MICL,PRO34150,CLL1,DCAL-2,CD303,<...	Human	HEK293 Cells
	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is 51.61 kDa and the accession number is EAW96132.1.
TMPY-06865	CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (His) D230024O04,C-type lectin domain family 12, member A...	Mouse	HEK293 Cells
	CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.12 kDa and the accession number is NP_808354.1.

重组蛋白

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02092

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc)

Cat.No: TMPK-01004

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Biotinylated

Cat.No: TMPK-01003

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, His)

Cat.No: TMPK-00995

Species: Mouse

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00548

Species: Cynomolgus

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled

Cat.No: TMPK-01005

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPK-01002

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His)

Cat.No: TMPK-01006

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06866

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (Avi & Fc), Biotinylated

Cat.No: TMPY-06881

Species: Human

Expression System: HEK293 Cells

CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06865

Species: Mouse

Expression System: HEK293 Cells

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