Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4047 |
Bisantrene
CL216942,比生群 |
Topoisomerase | DNA Damage/DNA Repair |
Bisantrene (CL216942) 是一种具有抗肿瘤活性的蒽基双腙,可靶向作用于真核生物的 II 型拓扑异构酶。它插入并破坏 DNA 的构型,导致 DNA 单链断裂、DNA-蛋白质交联和 DNA 复制的抑制。 | |||
T4047L |
Bisantrene HCl
CL216942,CL-216942,NSC-337766,CL 216942 |
Others | Others |
Bisantrene (CL-216942; NSC 337766) is a topoisomerase II poison and DNA intercalator. It can be used as a Rac1 inhibitor or model compound to study P-glycoprotein-mediated multi-drug resistance (MDR1). Bisantrene inserts and disrupts the configuration of |