Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7551 |
Belotecan hydrochloride
CKD-602 |
Topoisomerase | DNA Damage/DNA Repair |
Belotecan hydrochloride (CKD-602) 是一种合成的水溶性喜树碱衍生物和拓扑异构酶 I 抑制剂,具有潜在的抗肿瘤活性。 | |||
T36700 | CKD 602 | ||
Topoisomerase I inhibitor. Forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. Inhibits growth of a range of cancer cell lines in vitro, as well as of ovarian and leukemia tumors in vivo. |