Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7551 |
Belotecan hydrochloride
CKD-602 |
Topoisomerase | DNA Damage/DNA Repair |
Belotecan hydrochloride (CKD-602) 是一种合成的水溶性喜树碱衍生物和拓扑异构酶 I 抑制剂,具有潜在的抗肿瘤活性。 | |||
T36700 | CKD 602 | ||
Topoisomerase I inhibitor. Forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. Inhibits growth of a range of cancer cell lines in vitro, as well as of ovarian and leukemia tumors in vivo. | |||
T62435 |
Belotecan
|
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Belotecan (CKD-602 free base) 是一种 DNA topoisomerase I 抑制剂。Belotecan 能够阻滞细胞周期,并诱导细胞凋亡。Belotecan 是一种具有抗肿瘤作用的喜树碱衍生物,能够用于研究癌症。 |