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Cat. No. Product Name Target Signaling Pathways
T1528 Azasetron hydrochloride

Y-25130 hydrochloride,Y-25130 HCl,盐酸阿扎司琼,Azasetron HCl

5-HT Receptor GPCR/G Protein; Neuroscience
Azasetron hydrochloride (Y-25130 HCl) 是一种苯甲酰胺的衍生物,是有效的、选择性的5-HT3受体拮抗剂,可用于化疗引起的恶心呕吐研究。
T3716 Rolapitant

罗拉吡坦,SCH619734,罗拉匹坦

Neurokinin receptor GPCR/G Protein; Neuroscience
Rolapitant (SCH619734) 是一种高效选择性具有口服活性的神经激肽 1 受体抑制剂,Ki 值为0.66 nM。
T22393 Palonosetron

RS25259,帕洛诺司琼,RS 25259 197

5-HT Receptor GPCR/G Protein; Neuroscience
Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
T68371 Rolapitant hydrochloride hydrate

Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. Upon oral administration, rolapitant competitively binds to and blocks the activity of the NK1-receptor in the central nervous system, thereby inhibiting the binding of the endogenous ligand, substance P (SP). This may prevent both SP-induced emesis and chemotherapy-induced nausea and vomiting (CINV). The interaction of ...

化合物

Azasetron hydrochloride
Cat.No: T1528
Synonym: Y-25130 hydrochloride,Y-25130 HCl,盐酸阿扎司琼,Azasetron HCl
Target: 5-HT Receptor
Rolapitant
Cat.No: T3716
Synonym: 罗拉吡坦,SCH619734,罗拉匹坦
Target: Neurokinin receptor
Palonosetron
Cat.No: T22393
Synonym: RS25259,帕洛诺司琼,RS 25259 197
Target: 5-HT Receptor
Rolapitant hydrochloride hydrate
Cat.No: T68371
Synonym:
Target:
TargetMol Loading
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