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Cat. No. Product Name Target Signaling Pathways
T17164 Trimetrexate

三甲曲沙,CI-898

Others Others
Trimetrexate is an effective competitive inhibitor of bacterial, protozoan, and mammalian dihydrofolate reductase.
T70304 CI-898 HCl

CI-898 HCl is a lipophilic antifolate inhibitor of dihydrofolate reductase (DHFR). It has enhanced binding to DHFR in the presence of the cofactor NADPH. Cl-898 HCl inhibits cell growth and halts the cell cycle at the G1/S phase in L1210 mouse lymphocytic leukemia cells and is active against methotrexate-resistant cancer cell lines. It also enhances the activity of doxorubicin, cyclophosphamide, and 6-thioguanine (6-TG) in mice with advanced stage P338 leukemia.

化合物

Trimetrexate
Cat.No: T17164
Synonym: 三甲曲沙,CI-898
Target: Others
CI-898 HCl
Cat.No: T70304
Synonym:
Target:
TargetMol Loading
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