Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8780 |
AMG131
INT-131,AMG-131,CHS 131 |
PPAR | DNA Damage/DNA Repair; Metabolism |
AMG131 (CHS 131) 是一种新型非噻唑烷二酮(TZD) 选择性过氧化物酶体增殖物激活受体 (PPAR) γ 调节剂,可用于治疗 2 型糖尿病。 | |||
T68567 |
AMG-131 besylate
|
||
AMG-131 besylate is a hypoglycemic agent. It is a potent PPARγ partial agonist that displays robust glucose-lowering activity in rodent models of diabetes while exhibiting a reduced side-effects profile compared to marketed TZDs. |