Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00716 |
Cerberus 1/CER1 Protein, Human, Recombinant (HEK293, His)
DAN Domain Family Member 4,Cerberus,Cerber... |
Human | HEK293 Cells |
Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin/Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO/Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in respon... | |||
TMPY-00484 |
Cerberus 1/CER1 Protein, Human, Recombinant (His)
DAND4,cerberus 1, DAN family BMP antagonis... |
Human | Baculovirus Insect Cells |
Cerberus 1/CER1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is AAH69371.1. | |||
TMPK-00149 |
Fc epsilon RI alpha/FCER1a Protein, Human, Recombinant (His)
Fc-ε RI-α,Fc-epsilon RI-alpha,FCER1A,Fc-ep... |
Human | HEK293 Cells |
Known susceptibility genes to atopy and asthma have been identified by linkage or associations with clinical phenotypes, including total serum IgE levels. IgE-mediated sensitivity reactions require a high-affinity IgE receptor (FcepsilonRI), which immobilizes the immunoglobulin on the surface of the effector cells, mostly mast cells and basophils. Similarly to the previously investigated beta subunit of the receptor, FCER1A is a good candidate for a quantitative trait locus (QTL) in allergic dis... |