Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05291 |
CD57/B3gat1 Protein, Human, Recombinant (mFc)
LEU7,NK1,beta-1,3-glucuronyltransferase 1,HNK1,GLCATP,NK-1,β... |
Human | HEK293 Cells |
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited downstream integrin signaling, which was mimicked by knockdown of the core chondroitin sulfate synthesis enzymes β-1,3-glucuronyltransferase 1 (B3GAT1) and chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1). | |||
TMPJ-00220 |
B3GAT1 Protein, Human, Recombinant (His)
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)... |
Human | HEK293 Cells |
B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. It adds a glucuronic residue to the terminal lactosamine residue (Gal beta 14GlcNAc) of a glycoprotein or glycolipid, which can be further sulfated to become the HNK1 epitope, a unique trisaccharide structure, HSO3-3GlcA beta 1-3Gal beta 1-4GlcNAc. The enzyme activity was found to be enhanced in the presence of sphingomyelin an... | |||
TMPK-00137 |
ULBP-2 Protein, Human, Recombinant (His & Avi), Biotinylated
ALCAN-α,NKG2DL2,ULBP2,ALCAN-alpha,ULBP-2/5/6,N2DL2,RAET1L,RA... |
Human | HEK293 Cells |
ULBP2 expression was however linked to expression of mature CD57() NK cells. In particular, expression of ULBP2 was strongest on those NK cells that had evidence of recent activation and proliferation. We suggest that ULBP2 could be used to identify recently activated "mature" NK cells. |