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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14911 |
CD2665
|
Retinoid Receptor | Metabolism |
CD2665 是一种具有口服活性的视黄酸受体 (RAR) 拮抗剂。对于 RARγ 和 RARβ,Kis 为 110 nM 和 306 nM。 | |||
T76922 | Begelomab | ||
Begelomab (SAND-26) 是一种针对 DPP-4/CD26的鼠IgG2b 单克隆抗体。 Begelomab 可用于严重难治性特发性炎症性肌病的研究。 | |||
T20028 |
Janumet
Efficib,Janumet XR,Metformin / sitagliptin,Metformin hydrochloride mixture with sitagliptin phosphate |
||
Metformin hydrochloride mixture with sitagliptin phosphate is an AMP-activated protein kinase stimulant. It is also a CD26 antigen inhibitor, Gluconeogenesis inhibitor, and Glucose modulator. | |||
T36651 |
Anti-MERS-2E6 mAb
Anti-MERS-2E6 mAb |
||
Anti-MERS-2E6 mAb (MERS-2E6), a human IgG1 neutralizing antibody, is expressed in CHO cells. It effectively competes with the virus Spike protein for binding to the CD26 receptor, consequently inhibiting viral invasion into host cells. | |||
T78751 |
DG1
|
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DG1(化合物8Nc)是一种Thymidylate Synthase(TS)抑制剂,具有抑制NSCLC细胞的血管生成和代谢重编程作用。此外,DG1还能有效下调CD26、ET-1、FGF-1和EGF的表达,并在A549异种移植小鼠模型中显著抑制肿瘤组织的增殖。 | |||
T37861 |
Talabostat
|
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Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00221 |
DPP4/CD26 Protein, Mouse, Recombinant (hFc)
dipeptidylpeptidase 4,Dpp-4,Cd26,THAM |
Mouse | HEK293 Cells |
DPP4/CD26 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112.9 kDa and the accession number is P28843. | |||
TMPY-00778 |
DPP4/CD26 Protein, Human, Recombinant (hFc)
DPPIV,TP103,ADABP,CD26,ADCP2,dipeptidylpep... |
Human | HEK293 Cells |
DPP4/CD26 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P27487. | |||
TMPY-00779 |
DPP4/CD26 Protein, Human, Recombinant
TP103,CD26,ADCP2,DPPIV,ADABP,dipeptidylpep... |
Human | HEK293 Cells |
DPP4/CD26 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 85.4 kDa and the accession number is P27487. | |||
TMPY-00122 |
DPP4/CD26 Protein, Human, Recombinant (His)
TP103,ADABP,CD26,ADCP2,DPPIV,dipeptidylpep... |
Human | HEK293 Cells |
DPP4/CD26 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is P27487. | |||
TMPY-00074 |
DPP4/CD26 Protein, Mouse, Recombinant (His)
dipeptidylpeptidase 4,Dpp-4,Cd26,THAM |
Mouse | HEK293 Cells |
DPP4/CD26 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.9 kDa and the accession number is P28843. | |||
TMPK-00377 |
DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
DPP4,DPPIV,ADCP2,CD26,ADABP,TP103,EC 3.4.1... |
Cynomolgus,Rhesus | HEK293 Cells |
CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent. | |||
TMPH-03279 |
DPP4/CD26 Protein, Rat, Recombinant (His & SUMO)
Dpp4,Dipeptidyl peptidase IV,DPP IV,CD26,D... |
Rat | E. coli |
Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular ... | |||
TMPY-04046 |
DPP4/CD26 Protein, Cynomolgus, Recombinant
dipeptidylpeptidase 4 |
Cynomolgus | HEK293 Cells |
DPP4/CD26 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 84.6 kDa and the accession number is F6VRB0. | |||
TMPY-03952 |
DPP4/CD26 Protein, Cynomolgus, Recombinant (hFc)
dipeptidylpeptidase 4 |
Cynomolgus | HEK293 Cells |
DPP4/CD26 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112.9 kDa and the accession number is F6VRB0. | |||
TMPY-04251 |
DPP4/CD26 Protein, Cynomolgus, Recombinant (His)
dipeptidylpeptidase 4 |
Cynomolgus | HEK293 Cells |
DPP4/CD26 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is XP_005573375.1. |