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Search Results for " cd133 "

3

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T60661	CP681301
	CP681301 是CDK5的有效抑制剂，具有抗增殖活性。CP681301 在果蝇中表现出抗肿瘤活性。CP681301 降低神经胶质瘤干细胞中 CD133、OLIG2、SOX2、KI67、pCDK5 蛋白水平的表达。CP681301 减少小鼠胶质瘤异种移植物的自我更新。
T69241	MEISi-1
	MEISi-1 is a novel MEIS inhibitor (MEISi), significantly inhibiting MEIS-luciferase reporters in vitro and inducing murine (LSKCD34low cells) and human (CD34+, CD133+, and ALDHhi cells) HSC self-renewal ex vivo.
T71998	673-A
	673-A is an aldehyde dehydrogenase (ALDH1A) inhibitor that depletes CD133+ cancer stem cells (CSC) in ovarian cancer cell lines. 673-A triggers necroptosis in ovarian CSCs and induces expression of mitochondrial uncoupling proteins (UCP). 673-A also overcomes chemotherapy resistance in vivo.

化合物

Cat.No: T60661

Cat.No: T69241

Cat.No: T71998

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00001	CD133/PROM1 Protein-VLP, Human, Recombinant (His) Proml1,Prom1,CD133,Prominin-like protein 1...	Human	HEK293 Cells
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner. CD133/PROM1 Protein...
TMPH-02842	CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO) CD133,Prom1,Prominin-like protein 1,Prom,P...	Mouse	E. coli
	May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
TMPY-03690	CD133/PROM1 Protein, Rat, Recombinant (mFc) prominin 1	Rat	HEK293 Cells
	CD133/PROM1 Protein, Rat, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60 kDa and the accession number is Q7TSL4.
TMPY-03691	CD133/PROM1 Protein, Rat, Recombinant (His) prominin 1	Rat	HEK293 Cells
	CD133/PROM1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.10 kDa and the accession number is Q7TSL4.
THMH-00001	CD133/PROM1 Recombinant,Human(Yeast expression,His)

TMPY-01345	ACBD6 Protein, Human, Recombinant (His) acyl-CoA binding domain containing 6	Human	Baculovirus Insect Cells
	Human acyl-coenzyme A binding domain-containing member 6 (ACBD6) is a modular protein that carries an acyl-CoA binding domain at its N terminus and two ankyrin motifs at its C terminus. In mammals, there are six members of the acyl-CoA binding domain-containing (ACBD) family, and their annotation is not uniform. All six ACBD proteins contain an ACB domain at the N terminus, but they do not share significant homology at the C-terminal region. ACBD6 is a 32 kDa protein that is predicted by sequenc...
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc) artemin,neublastin	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons. It a...

重组蛋白

CD133/PROM1 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-00001

Species: Human

Expression System: HEK293 Cells

CD133/PROM1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02842

Species: Mouse

Expression System: E. coli

CD133/PROM1 Protein, Rat, Recombinant (mFc)

Cat.No: TMPY-03690

Species: Rat

Expression System: HEK293 Cells

CD133/PROM1 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03691

Species: Rat

Expression System: HEK293 Cells

CD133/PROM1 Recombinant,Human(Yeast expression,His)

Cat.No: THMH-00001

Expression System:

ACBD6 Protein, Human, Recombinant (His)

Cat.No: TMPY-01345

Species: Human

Expression System: Baculovirus Insect Cells

Artemin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

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