1
6
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61621 |
IMMH001
|
||
IMMH001, also known as SYL930, is an orally active compound that exhibits potent selectivity as an agonist for the S1P1 receptor, which is the sphingosine-1-phosphate receptor 1. This compound effectively reduces the levels of various chemokines and proinflammatory cytokines, such as IL-1β, IL-5, IL-18, IP10, CCL3, and CCL5. IMMH001 finds utility in research focused on rheumatoid arthritis (RA) [1] [2]. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04037 |
MIP-1 alpha/CCL3 Protein, Rat, Recombinant
chemokine (C-C motif) ligand 3,MIP-1 α |
Rat | E. coli |
MIP-1 alpha/CCL3 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 kDa and the accession number is P50229. | |||
TMPY-00649 |
MIP-1 alpha/CCL3 Protein, Human, Recombinant (His)
LD78α,chemokine (C-C motif) ligand 3,MIP-1-alpha,G0... |
Human | P. pastoris (Yeast) |
MIP-1 alpha/CCL3 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.2 kDa and the accession number is A0N0R1. | |||
TMPJ-00005 |
CCL3 Protein, Human, Recombinant
MIP-1-Alpha,CCL3,MIP-1-α,Small-Inducible C... |
Human | E. coli |
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3. | |||
TMPJ-00831 |
CCL3 Protein, Mouse, Recombinant (His)
LD78 α,MIP-1 α,MIP1-a,MIP-1 alpha,LD78 alpha,chemokine (C-C ... |
Mouse | E. coli |
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, smooth muscle cells, and epithelial cells. Mature mouse CCL3 shares 73%, 91%, and 82% amino acid sequence identity with human, rat, and cotton rat CCL3, respectively. CCL3 exerts its biological functions through interactions with CCR1, CCR3, and CCR5. It is cleared from the extra... | |||
TMPY-03231 |
MIP-1 alpha/CCL3 Protein, Mouse, Recombinant
MIP-1α,LD78α,chemokine (C-C motif) ligand 3,AI3... |
Mouse | E. coli |
MIP-1 alpha/CCL3 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.01 kDa and the accession number is P10855. | |||
TMPJ-00873 |
CCL3L1 Protein, Human, Recombinant (His)
CCL3L3,G0S19-2,CCL3<... |
Human | HEK293 Cells |
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The processed form LD78-beta (3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor o... |