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Cat. No. Product Name Target Signaling Pathways
T38279 C2-8

C2-8

C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington's disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2...
T60078 NSC2805

2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol

Others Others
NSC2805 是 WWP2 的抑制剂,WWP2 是一种 E3 泛素连接酶,IC50 为 0.38 μM。 NSC2805 可用于抗癌研究。
T2629 UNC2881

TAM Receptor Tyrosine Kinase/Adaptors
UNC2881 是一种特异性Mer 激酶抑制剂,可抑制稳态的Mer 激酶磷酸化,其IC50=22 nM。
T28931 TC-AC28

TC AC28

TC-AC28 is a novel potent and selective Brd2(2) ligand.
T68804 LC28

LC28 is a novel inhibitor of STAT3 signaling, suppressing survival of cisplatin-resistant ovarian cancer cells.
T37461 EOS (d18:1/32:1/18:2)

EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the ver...

化合物

C2-8
Cat.No: T38279
Synonym: C2-8
Target:
NSC2805
Cat.No: T60078
Synonym: 2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol
Target: Others
UNC2881
Cat.No: T2629
Synonym:
Target: TAM Receptor
TC-AC28
Cat.No: T28931
Synonym: TC AC28
Target:
LC28
Cat.No: T68804
Synonym:
Target:
EOS (d18:1/32:1/18:2)
Cat.No: T37461
Synonym:
Target:
TargetMol Loading
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