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Cat. No. Product Name Target Signaling Pathways
T37457 C18 L-threo Ceramide (d18:1/18:0)

C18 L-threo Ceramide (d18:1/18:0)

C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.21 mol% (16.8 μM).
T37455 C18 D-threo Ceramide (d18:1/18:0)

C18 D-threo Ceramide (d18:1/18:0)

C18 D-threoCeramide (d18:1/18:0) is a synthetic ceramide and stereoisomer of C18 ceramide .1It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50value of 16.6 μM.2[Matreya, LLC. Catalog No. 1855] 1.Koolath, S., Murai, Y., Suga, Y., et al.Chiral combinatorial preparation and biological evaluation of unique ceramides for inhibition of sphingomyelin synthaseChirality32(3)308-313(2019) 2.Usta, J., El Bawab, S., Roddy, P., et al.Structural requirements of ceramide and sphingosine bas...
T37456 C18 L-erythro Ceramide (d18:1/18:0)

C18 L-erythro Ceramide (d18:1/18:0)

C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide . It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 0.11 mol% (8.8 μM).
T83880 C18 Ceramide-1-phosphate (d18:1/18:0) ammonium

Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate

C18 Ceramide-1-phosphate (d18:1/18:0) 是一种在鼠皮肤中发现的长链ceramide-1-phosphate。它能在0.5至5 µM的浓度范围内促进分离的小鼠骨髓来源的多能间充质细胞和人脐静脉内皮细胞(HUVECs)的迁移。与胰腺癌干细胞相比,CFPAC-1胰管腺癌细胞中C18 Ceramide-1-phosphate (d18:1/18:0)的水平有所增加。在Langendorff分离的灌流小鼠心脏的离体缺血模型中,心肌中C18 ceramide-1-phosphate (d18:1/18:0)的水平有所增加。
T35806 N-Stearoylsphingosine

C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide

Phosphatase Metabolism
N-Stearoylsphingosine (Cer(d18:1/18:0)) 是一种广泛存在真核生物体内的酰胺类化合物,通过干扰PP2A与PP2A抑制剂2的结合来增强蛋白质磷酸酶2A(PP2A)活性,导致Akt去磷酸化。N-Stearoylsphingosine 可用于研究前列腺癌。

化合物

C18 L-threo Ceramide (d18:1/18:0)
Cat.No: T37457
Synonym: C18 L-threo Ceramide (d18:1/18:0)
Target:
C18 D-threo Ceramide (d18:1/18:0)
Cat.No: T37455
Synonym: C18 D-threo Ceramide (d18:1/18:0)
Target:
C18 L-erythro Ceramide (d18:1/18:0)
Cat.No: T37456
Synonym: C18 L-erythro Ceramide (d18:1/18:0)
Target:
C18 Ceramide-1-phosphate (d18:1/18:0) ammonium
Cat.No: T83880
Synonym: Ceramide-1-phosphate (d18:1/18:0),N-octadecanoyl-D-erythro-Sphingosine-1-phosphate,C18 Ceramide-1-phosphate,C18 C1P,CerP(d18:1/18:0),N-stearoyl-D-erythro-Sphingosine-1-phosphate
Target:
N-Stearoylsphingosine
Cat.No: T35806
Synonym: C(18:0)/C(18:1),Cer(d18:1/18:0),C18 Ceramide (d18:1/18:0),C18 Ceramide
Target: Phosphatase
TargetMol Loading
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