Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16789 |
Rosoxacin
罗索沙星,Acrosoxacin |
Antibacterial; Antibiotic | Microbiology/Virology |
Rosoxacin (Acrosoxacin) 是具有口服活性的喹诺酮类抗生素,具有广谱的抗菌活性,抑制革兰氏阴性菌,包括淋病奈瑟氏球菌(MIC90=0.03 mg/ml)。它在尿路感染中有应用的潜能。 | |||
T70103 | KSK213 | ||
KSK213 is a potent inhibitor of Chlamydia trachomatis Infectivity (EC50 = 60 nM). KSK213 potently inhibited multiple serovars of C. trachomatis while not affecting the growth of key species from the commensal flora or host cell viability at 25 μM. | |||
T16749 |
Rifalazil
利福拉齐,KRM-1648,ABI-1648 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Rifalazil is a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis (MIC: 0.00025 to 0.0025 μg/ml). | |||
T37730 |
Saccharocarcin A
|
||
Saccharocarcin A is an antibiotic originally isolated from S. aerocolonigenes subsp. antibiotica. It is active against M. luteus, S. aureus, E. coli, P. aeruginosa, and C. albicans in a disc assay. Saccharocarcin A inhibits C. trachomatis infection by 88% without inducing cytotoxicity in McCoy cells when used at a concentration of 0.5 μg/ml. | |||
T37677 |
3-hydroxy Docosanoic Acid
|
||
3-hydroxy Docosanoic acid is a hydroxylated form of the 22-carbon saturated docosanoic acid . It is found in lipopolysaccharides from C. trachomatis and C. psittaci and in S. synnaedendra. 3-hydroxy Docosanoic acid, in the form of an acyl-CoA metabolite, is an intermediate in fatty acid chain elongation from arachidic acid to docosanoic acid (C22:0). |