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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1767 |
BMH-21
BMH21 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
BMH-21 是一种小分子 DNA 嵌入剂,可结合核糖体 DNA 并抑制 RNA 聚合酶 I (Pol I) 转录,具有抗癌活性。 | |||
T23804 |
BMH-9
BMH 9 |
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BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types. | |||
T23803 |
BMH-23
BMH23,BMH 23 |
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BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types. | |||
T23802 |
BMH-22
BMH22 |
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BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types. | |||
T26840 |
BMH-7
BMH7 |
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BMH-7 is a p53 activator with potent antitumor activity. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01865 |
BLMH Protein, Mouse, Recombinant (His)
Bh,bleomycin hydrolase,Bmh,AI035728 |
Mouse | E. coli |
The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide antica... |