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Cat. No.	Product Name	Target	Signaling Pathways
T6032	Birabresib OTX-015,OTX015 （MK 8628/Birabresib）,MK-8628	Epigenetic Reader Domain	Chromatin/Epigenetic
	Birabresib (MK-8628) 是一种 BRD2/3/4抑制剂，IC50值为 92 到 112 nM 之间，具有潜在的抗肿瘤活性。
T69963	Birabresib dihydrate
	Birabresib dihydrate was initially developed by Mitsubishi Tanabe Pharma Corporation, but then was licensed by OncoEthix, privately held biotechnology company. OTX015 is a selective bromodomains: BRD2, BRD3, and BRD4 inhibitor and inhibits their binding to AcH4. Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including methyltransferases, HATs and transcription factors and regulate diverse biological processes from cell proliferation and dif...