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15
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38476 |
Metallo β-lactamase ligand 1
|
Antibacterial | Microbiology/Virology |
Metallo β-lactamase ligand 1 是B 类β-内酰胺酶的抑制剂,具有抗菌活性。 | |||
T19206 |
β-Lactamase-IN-1
4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1 |
Antibacterial | Microbiology/Virology |
β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) 是一种 β-Lactamase 抑制剂,针对淋病奈瑟菌的感染。 | |||
T35427 |
β-Lactamase-IN-2
|
Antibacterial | Microbiology/Virology |
β-Lactamase-IN-2 是 β-内酰胺酶的有效抑制剂。β-Lactamase-IN-2显示出抗菌活性。 | |||
T14979 |
Clavulanate lithium
Clavulanic acid lithium,克拉维酸锂 |
Antibacterial | Microbiology/Virology |
Clavulanate lithium (Clavulanic acid lithium) 是一种β-lactamase 的高效抑制剂,可作抗生素。 | |||
T38955 |
β-Lactamase-IN-4
|
||
β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections. | |||
T38956 |
β-Lactamase-IN-5
|
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β-Lactamase-IN-5, a β-lactamase inhibitor isolated from compound 720, holds significant potential for studying bacterial infections. | |||
T39865 |
β-Lactamase-IN-6
|
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β-Lactamase-IN-6 is a β-Lactamase inhibitor that shows high antibacetrial activity. | |||
T1631 |
Sulbactam
CP45899,舒巴坦,舒巴坦酸 |
Antibacterial; Antibiotic | Microbiology/Virology |
Sulbactam (CP45899) 是一种竞争性、不可逆的 β-内酰胺酶抑制剂,抑制耐多药不动杆菌-鲍曼不动杆菌复合物。它具有抗菌活性。 | |||
T15047 |
Dacisteine
N,S-Diacetyl-L-cysteine,达西司坦 |
Others | Others |
Dacisteine (N,S-Diacetyl-L-cysteine) 是 New Delhi metallo-beta-lactamase-1 (NDM-1) 的抑制剂 (IC50 = 1000 μM)。 | |||
T0234 |
Methicillin sodium salt
Methicillin sodium,Meticillin sodium,甲氧西林钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Methicillin sodium salt 是β-内酰胺抗生素,抑制参与肽聚糖合成的青霉素结合蛋白。 | |||
T1143 |
Carbenicillin disodium
BRL-2064,羧苄青霉素钠,Sodium carbenicillin |
Cell wall; Antibacterial; Antibiotic | Immunology/Inflammation; Microbiology/Virology |
Carbenicillin disodium (BRL-2064) 作用于细菌细胞壁合成的最后阶段,是β-内酰胺青霉素衍生物。 | |||
T5570 |
Cephalothin
头孢噻吩,Cephalotin acid |
Antibacterial; Antibiotic | Microbiology/Virology |
Cephalothin 是一种 β-内酰胺抗生素,抑制 C 类 β-内酰胺酶活性的 Ki 值为 0.32 µM。 | |||
T1031 |
Cloxacillin sodium monohydrate
Cloxacillin Sodium,Bactopen,氯唑西林钠一水合物 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cloxacillin sodium monohydrate (Cloxacillin Sodium) 有抗菌作用,对Staphylococcus aureus25923 的最小抑菌浓度为256 mg/L。 | |||
T1405 |
Cefditoren pivoxil
头孢妥仑匹酯,ME 1207,Cefditoren pivaloyloxymethyl ester,Cefditoren pivoxyl |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefditoren pivoxil (ME 1207) 是一种半合成、广谱、β-内酰胺酶耐药的第三代头孢菌素抗生素,具有杀菌活性。 | |||
T0868 |
Cefepime Dihydrochloride Monohydrate
Cefepime HCl,头孢吡肟二盐酸盐一水合物 |
Antibacterial; Antibiotic; Antifection | Microbiology/Virology |
Cefepime Dihydrochloride Monohydrate (Cefepime HCl) 是一种广谱头孢菌素,对革兰氏阳性菌和革兰氏阴性菌有更高的覆盖率。 | |||
T6268 |
Ceftiofur hydrochloride
头孢噻呋盐酸盐,Ceftiofur HCl,U-67279A,Excenel hydrochloride |
Antibacterial; Antibiotic | Microbiology/Virology |
Ceftiofur hydrochloride (U-67279A) 是头孢噻呋的盐酸盐形式,是一种β-内酰胺酶稳定的半合成广谱头孢菌素,具有抗菌活性。 | |||
T19860 |
Clavulanic Acid
BRL 14151,MM-14151,MM 14151,RX-10100,MM14151,BRL14151,BRL-14151 |
Antibacterial; Antifungal | Microbiology/Virology |
Clavulanic Acid(RX-10100) 是一种由生物体克拉维链霉菌产生的主要β-内酰胺类抗生素,是一种强效的细菌 β-内酰胺酶抑制剂,用于研究细菌引起的感染。Clavulanic Acid 具有广谱的生物活性,对多种革兰氏阳性和革兰氏阴性细菌均有活性。 | |||
T1063 |
Ticarcillin disodium
Ticarpen,Ticarcillin disodium salt,替卡西林二钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ticarcillin disodium (Ticarpen) 主要用于抗革兰氏阴性菌, 特别是绿脓杆菌, 也是少数可研究嗜麦芽感染的抗生素。 | |||
T1224 |
Cefuroxime sodium
Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素,增加了对 β-内酰胺酶的稳定性。 | |||
T26906 | Brobactam | ||
Brobactam is a beta lactamase inhibitor with antibacterial activity. | |||
T12604 |
Xeruborbactam
QPX7728 |
Others | Others |
QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase. | |||
T71613 | MK-8712 | ||
MK-8712 is a monobactam beta-lactamase inhibitor. | |||
T25355 |
Durlobactam
|
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Durlobactam is a drug candidate for beta-lactamase inhibitor. | |||
T69300 | AVE-1330A free acid | ||
AVE-1330A free acid is a broad-spectrum non-beta-lactam beta-lactamase inhibitor. | |||
T69272 |
AM-112
|
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AM-112 is an Oxapenem compound which possesses potent beta-lactamase-inhibitory properties. | |||
T69299 |
AVE-1330A sodium
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AVE-1330A sodium is a beta-Lactamase inhibitor. | |||
T75391 |
Penicillinase
|
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Penicillinase 是一种 β-内酰胺酶。β-内酰胺酶通过水解特征性四元 β-内酰胺环的肽键使抗生素失效,从而使 β-内酰胺抗生素失活。 | |||
T28669 |
SB 202742
SB202742,SB-202742 |
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SB 202742 is an inhibitor of beta-lactamase, it is isolated from Spondias mombin. | |||
T28670 |
SB 204070 hydrochloride
SB 204070 HCl |
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SB 204070 hydrochloride is an inhibitor of beta-lactamase, it is isolated from Spondias mombin. | |||
T69999 |
Nacubactam monohydrate
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Nacubactam monohydrate is a beta-lactamase inhibitor used for bacterial infections. | |||
T73438 |
MK-3402
|
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MK-3402 是一种metallo-beta-lactamase 抑制剂。MK-3402 可用于细菌研究。 | |||
TMIH-0530 |
Sulbactam-d2
|
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Sulbactam-d2 是 Sulbactam 的氘代化合物。Sulbactam 的 CAS 号为 68373-14-8。Sulbactam是一种竞争性、不可逆的 β-内酰胺酶抑制剂,抑制耐多药不动杆菌-鲍曼不动杆菌复合物。它具有抗菌活性。 | |||
T27386 |
FR-295389
FR-295389 Free Base,FR295389 |
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FR-295389 is a cephalosporin. FR-295389 shows effective antibacterial activity against metallo-beta-lactamase (MBL)-producers in vitro. | |||
T39287 |
Ledaborbactam
|
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Iedaborbactam, as a beta-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections. | |||
T21163 |
Cloxacillin Sodium
BRL-1621 sodium salt,Ankerbin,Cloxapen,Austrastaph,BRL 1621 sodium salt |
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Cloxacillin Sodium, a chlorinated derivative of Oxacillin, is a semi-synthetic antibiotic. Cloxacillin is used for the treatment of infections caused by species of staphylococci which produce beta-lactamase. | |||
T12524 |
Potassium clavulanate cellulose
Potassium clavulanate:cellulose (1:1) |
Others | Others |
Potassium clavulanate cellulose is a mixture of potassium clavulanate and cellulose, is an inhibitor of beta-lactamase. | |||
T22433 |
Sulopenem
CP-70429,硫培南 |
Others | Others |
Sulopenem, an orally active, potent inhibitor of beta-lactamase, is a parenteral penem antibiotic with broad-spectrum activities against Gram-negative and Gram-positive bacteria. | |||
T21384 |
Dicloxacillin
Dicloxacilina,Dicloxacycline,Dicloxacillinum,Dicloxacilline,Diclocil,Dynapen |
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Dicloxacillin (INN), a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. | |||
T1023 |
Cefoxitin sodium
Cenomycin,MK-306,头孢西丁钠,Betacef,Merxin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefoxitin sodium (Betacef) 是一种头霉素类抗生素。Cefoxitin 干扰细胞壁合成。它对革兰氏阴性和革兰氏阳性菌有活性。 | |||
T1190L |
Cefmenoxime
A-50912,A 50912,A50912,AB 50912 |
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Cefmenoxime is a cephalosporin antibiotic administered intravenously or intramuscularly. It is an effective inhibitor of Enterobacteriaceae and is resistant to beta-lactamase-initiated hydrolysis. It is active against most common gram-positive and gram-ne | |||
T72261 | Metallo-β-lactamase-IN-9 | ||
Metallo-β-lactamase-IN-9 (Compound 23) 是一种高效的泛金属-β-内酰胺酶 (MBL) 抑制剂,其对 NDM-1、VIM-1 和 IMP-1 的抑制活性表现在 IC50 值上,分别为 35 nM、269 nM 和 369 nM。 | |||
T73668 |
Sanfetrinem sodium
|
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Sanfetrinem (GV104326) sodium,作为一种β-内酰胺酶稳定的抗生素(antibiotic),对革兰氏阳性菌和革兰氏阴性菌展现出广泛的抗菌活性。 | |||
T68938 |
Cefmenoxime sodium
|
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Cefmenoxime sodium is the ssalt form of Cefmenoxime (free base), a cephalosporin antibiotic administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms. It is a potent inhibitor of Enterobacteriaceae, and is resistant to beta-lactamase-initiated hydrolysis. The drug has a high success rate against many types of infection. | |||
T70621 |
Cefditoren Pivoxil HCl
|
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Cefditoren Pivoxil is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefditoren pivoxil is a prodrug that is rapidly hydrolyzed by intestinal esterases during absorption to the microbiologically active cefditoren, an active aminothiazolyl cephalosporin. Cefditoren inactivates penicillin binding proteins (PBPs) thereby interfering with peptidoglycan synthesis and inhibiting bacterial cell wall synthesis. |
Cat. No. | Product Name | Species | Expression System |
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TMPH-00588 |
Beta-lactamase Protein, E. coli, Recombinant (His & SUMO)
ampC,Cephalosporinase,ampA,Beta-lactamase |
E. coli | E. coli |
This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | |||
TMPH-03164 |
Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Beta-lactamase OXA-10,bla,Beta- |
Pseudomonas aeruginosa | E. coli |
Hydrolyzes both carbenicillin and oxacillin. Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.5 kDa and the accession number is P14489. | |||
TMPH-00584 |
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)
men1,Beta-lactamase MEN-1,Cefotaximase 1,<... |
E. coli | E. coli |
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. | |||
TMPH-03165 |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)
Beta-lactamase,ampC,ampA,Cephalosporinase |
Pseudomonas aeruginosa | E. coli |
Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735. | |||
TMPH-00585 |
Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)
Beta-lactamase MEN-1,Cefotaximase 1,bla,me... |
E. coli | P. pastoris (Yeast) |
Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins. | |||
TMPH-03474 |
Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant
bla,Beta-lactamase CTX-M-2,Cefotaximase 2 |
Salmonella typhimurium | E. coli |
Has cefotaxime-hydrolyzing activity. Beta-lactamase CTX-M-2 Protein, Salmonella typhimurium, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28.4 kDa and the accession number is P74841. | |||
TMPH-00586 |
Beta-lactamase TEM Protein, E. coli, Recombinant (His)
IRT-4,Penicillinase,TEM-2,TEM-16/CAZ-7,Beta-lac... |
E. coli | P. pastoris (Yeast) |
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lacta... | |||
TMPH-00587 |
Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)
IRT-4,TEM-16/CAZ-7,Penicillinase,Beta-lactamase... |
E. coli | E. coli |
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lacta... | |||
TMPJ-01157 |
LACTB2 Protein, Human, Recombinant (GST)
β-Lactamase-Like Protein 2,LACTB2,Beta- |
Human | E. coli |
β-Lactamase-like Protein 2 (LACTB2) is a number of the metallo-beta-lactamase superfamily.LACTB2 also belongs to the Glyoxalase II family. LACTB2 is 288 amino acids long with 8 zinc-binding domains. The LACTB2 gene is expressed at high levels and annotates structural defects or features in 4 cDNA clones. LACTB2 proteins are expected to have hydrolase activity and metal ion-binding functions. LACTB2 protein is found to localize in mitochondrion. Other functions of LACTB2 is yet unknown. | |||
TMPH-00019 |
BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO)
Class B carbapenemase NDM-1,NDM-1,NDM-1 metallo-beta |
Acinetobacter baumannii | E. coli |
BlaNDM-1 Protein, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E. coli with N-terminal 6xHis-SUMO tag. The predicted molecular weight is 22.0 kDa. Accession number: F8UNN7 | |||
TMPH-03602 |
BLIP Protein, S. clavuligerus, Recombinant (His & SUMO)
Beta-lactamase inhibitory protein,BLIP |
Streptomyces clavuligerus | E. coli |
Inhibits a wide variety of beta lactamases. BLIP Protein, S. clavuligerus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.5 kDa and the accession number is P35804. | |||
TMPH-02373 |
Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)
|
Klebsiella pneumoniae | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin. | |||
TMPH-03488 |
Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)
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Serratia marcescens | E. coli |
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.6 kDa and the accession number is P52699. | |||
TMPY-02288 |
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
HAGH1,GLO2,GLX2,hydroxyacylglutathione hydrolase,GLXII |
Human | E. coli |
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. HAGH belongs to the Metallo-beta-lactamase superfamily. HAGH is widely expressed in the kidney, liver, and other tissues. Diseases associated with HAGH include Hydroxyacyl Glutathio... | |||
TMPY-02447 |
Shiga toxin II subunit B Protein, E. coli, Recombinant (His)
|
E. coli | E. coli |
E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli, which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC). A total of 3222 outbreak cases (including 39 deaths) have been reported in northern Germany in May through June 2011. The outbreak strain was typed as an enteroaggregativ... |