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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T77188 Tifcemalimab

Tifcemalimab (JS004) 是一种人源化抗 BTLA(B 和 T 淋巴细胞衰减因子) 单克隆抗体。Tifcemalimab 通过与 BTLA 结合,阻断 HVEM-BTLA 的相互作用,从而阻断BTLA 介导的抑制信号通路。Tifcemalimab 可用于癌症的研究。

化合物

Tifcemalimab
Cat.No: T77188
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPK-01066 BTLA Protein, Human, Recombinant (His & Avi)

BTLA,BTLA1,FLJ16065,CD272,MGC129743

Human HEK293 Cells
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ...
TMPK-00530 BTLA Protein, Cynomolgus, Recombinant (His)

MGC129743,CD272,BTLA,BTLA1,FLJ16065

Cynomolgus HEK293 Cells
B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. BTLA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15...
TMPJ-00129 BTLA Protein, Human, Recombinant (His)

B- and T-Lymphocyte-Associated Protein,CD272,BTLA,B...

Human HEK293 Cells
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ...
TMPY-05828 BTLA Protein, Human, Recombinant (mFc)

BTLA1,B and T lymphocyte associated,CD272

Human HEK293 Cells
BTLA Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.09 kDa and the accession number is AAP44003.1.
TMPY-00175 BTLA Protein, Human, Recombinant (hFc)

BTLA1,B and T lymphocyte associated,CD272

Human HEK293 Cells
BTLA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.8 kDa and the accession number is Q7Z6A9-2.
TMPY-06930 BTLA Protein, Human, Recombinant (isoform1,hFc)

B and T lymphocyte associated,BTLA1,CD272

Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.47 kDa and the accession number is NP_861445.4.
TMPY-06913 BTLA Protein, Human, Recombinant (His & Avi), Biotinylated

BTLA1,B and T lymphocyte associated,CD272

Human HEK293 Cells
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17 kDa.
TMPY-06829 BTLA Protein, Human, Recombinant (isoform 1,mFc)

BTLA1,CD272,B and T lymphocyte associated

Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform 1,mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.56 kDa and the accession number is NP_861445.4.
TMPY-06922 BTLA Protein, Human, Recombinant (isoform1, His)

B and T lymphocyte associated,BTLA1,CD272

Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.19 kDa and the accession number is NM_181780.4.
TMPY-05416 BTLA Protein, Human, Recombinant (hFc & Avi), Biotinylated

BTLA1,CD272,B and T lymphocyte associated

Human HEK293 Cells
BTLA Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 40.6 kDa and the accession number is Q7Z6A9-2.
TMPY-04047 BTLA Protein, Rhesus, Recombinant (hFc)

B and T lymphocyte associated

Rhesus HEK293 Cells
BTLA Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.4 kDa and the accession number is A0A8J8XCU2.
TMPY-06923 BTLA Protein, Mouse, Recombinant (His)

B and T lymphocyte associated,A630002H24

Mouse HEK293 Cells
BTLA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.54 kDa and the accession number is AAI08964.1.
TMPY-03186 BTLA Protein, Mouse, Recombinant (hFc)

B and T lymphocyte associated,A630002H24

Mouse HEK293 Cells
BTLA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.75 kDa and the accession number is AAI08964.1.
TMPY-05101 BTLA Protein, Rhesus, Recombinant (His)

B and T lymphocyte associated

Rhesus HEK293 Cells
BTLA Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.3 kDa and the accession number is A0A8J8XCU2.
TMPY-00461 BTLA Protein, Rat, Recombinant (mFc)

B and T lymphocyte associated

Rat HEK293 Cells
BTLA Protein, Rat, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.4 kDa and the accession number is Q6PNM1-1.

重组蛋白

BTLA Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01066
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00530
Species: Cynomolgus
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00129
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05828
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00175
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1,hFc)
Cat.No: TMPY-06930
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06913
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (isoform 1,mFc)
Cat.No: TMPY-06829
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1, His)
Cat.No: TMPY-06922
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05416
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-04047
Species: Rhesus
Expression System: HEK293 Cells
BTLA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06923
Species: Mouse
Expression System: HEK293 Cells
BTLA Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03186
Species: Mouse
Expression System: HEK293 Cells
BTLA Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-05101
Species: Rhesus
Expression System: HEK293 Cells
BTLA Protein, Rat, Recombinant (mFc)
Cat.No: TMPY-00461
Species: Rat
Expression System: HEK293 Cells
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