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Cat. No. Product Name Target Signaling Pathways
T39612 BTK-IN-5

BTK-IN-5 is a covalent inhibitor of Bruton's tyrosine kinase (BTK) designed for the treatment of medical conditions including cardiovascular diseases, respiratory diseases, inflammation, and diabetes.
T62153 JAK3/BTK-IN-5

JAK3/BTK-IN-5 是一种 JAK3/BTK 的有效抑制剂。其中 BTK 和 JAK3 是自身免疫性疾病的两个关键的靶点。同时抑制 BTK/JAK3 信号通路具有协同效应。JAK3/BTK-IN-5 对 JAK3 激酶和/或 BTK 相关疾病具有潜在的研究价值。
T62716 BTK-IN-10

BTK-IN-10 是一种 BTK 的有效抑制剂,能够作用于野生型 BTK (IC50<5 nM) 或突变型 BTK (C481S) (IC50<5 nM)。
T39081 A 410099.1, amine-Boc

A-410099.1, also known as amine-Boc, serves as a functionalized IAP ligand instrumental in the synthesis of PROTACs, including those targeting BTK (specifically PROTACs 4 and 5).
T79292 PROTAC BTK Degrader-5

BTK Angiogenesis; Tyrosine Kinase/Adaptors
PROTACBTK Degrader-5 (compound 3e) 是一种BTK选择性降解剂,其在JeKo-1细胞中的DC50为7.0 nM。该化合物对CRBN新基态显示出无脱靶活性,且对淋巴瘤细胞表现出抗增殖效果,适用于恶性淋巴瘤的研究1。
T79812 BTK-IN-27

BTK Angiogenesis; Tyrosine Kinase/Adaptors
BTK-IN-27(示例8)作为一种BTK抑制剂,具有高效的IC50值为0.2 nM。在TMD8细胞中,该化合物展现出显著的抗增殖能力,IC50值低于5 nM。BTK-IN-27适用于癌症、淋巴瘤、白血病及免疫性疾病研究领域。
T39919 A 410099.1, amine-Boc hydrochloride

A 410099.1, amine-Boc hydrochloride, serves as a functionalized IAP (Inhibitor of Apoptosis Proteins) ligand instrumental in the synthesis of PROTACs (Proteolysis Targeting Chimeras), notably those targeting BTK (Bruton's Tyrosine Kinase), including PROTACs 4 and 5.

化合物

BTK-IN-5
Cat.No: T39612
Synonym:
Target:
JAK3/BTK-IN-5
Cat.No: T62153
Synonym:
Target:
BTK-IN-10
Cat.No: T62716
Synonym:
Target:
A 410099.1, amine-Boc
Cat.No: T39081
Synonym:
Target:
PROTAC BTK Degrader-5
Cat.No: T79292
Synonym:
Target: BTK
BTK-IN-27
Cat.No: T79812
Synonym:
Target: BTK
A 410099.1, amine-Boc hydrochloride
Cat.No: T39919
Synonym:
Target:
TargetMol Loading
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